QUANTUM ENGINEERING #66: LEPTIN Rx light codes

The video above gives you large brushstroke ideas of what quantum biology is to one of the pioneers in the field.  In this blog, I want to provide some other ideas that go further than his.  

Restriction of food intake to defined time periods is known to change the phase of the circadian clock and gene expression programs in humans, especially in primary metabolic organs such as the liver.  This is why fatty liver is a disease of light and not food.  When I read these papers in 2005 I wondered if this relationship exists within the liver what about the skin?   

The skin envelops our body.  It is where the environment acts to meet with our tissues.  For this reason, it should be a place where quantum biological processes can be found to help create the correct state for the "trickery" of nature to work with our cells.  

One of the most counterintuitive facts in skin biology is that AM light, dominated by red light with a paucity of UV, somehow protects the skin from future UV skin damage.  This fact tells us that some trickery is happening inside the skin's tissues, and red light photons induce this trickery.  Might there be some other trickery with the skin about another solar signal to protect it from UV light?  

WHY DOES THE LEPTIN RX have this peculiar relationship to breakfast timing?  

Food, at its core, is matter that encodes information about light via photosynthesis.  Because of this insight, I began to examine how the informational bar code in food might alter the transcriptome of the skin.  What I found was stunning.  Light and injury affects all the clock genes in our skin.  With that the Age of Light began in my head.  

When I went deeper into this rabbit hole I also found out I could use hair as a measure of disease reversal.  If you go back and re-read the Leptin Rx go look at what it says about sweating and hair return.  Now you are beginning to see the wisdom of that simple blog.  

I found that time-restricted feeding shifts the phase and alters the amplitude of the skin's circadian clock mechanism in humans.  This is why the 30-minute window is part of the Leptin Rx.  Moreover, time-restrictive feeding affects the expression of approximately 10% of the skin transcriptome.  What does it do?  It mimics the effect of red light on the skin concerning UV tolerance.  In other words, if you eat at the right time, UV light loses its toxicity for the skin!  

What is the food trickery I built into the Leptin Rx really about?  

Eating breakfast within 30 minutes of sunrise creates a time-restrictive feeding window designed to increase the skin's ability to upregulate the DNA repair apparatus for UV light.  , Many people still have not realized that many skin-expressed genes are acutely regulated by food intake in the morning. AM sunrise is required to improve the fidelity of the circadian mechanism.  The circadian clock is required to reset cells to the default state for daily rhythms in DNA synthesis in epidermal progenitor cells.  I then read this paper in 2015, and it told me my hunches ten years earlier were correct.

This paper implied that our exterior tissues had to have a mechanism built into them to control the circadian clocks of the gut.  It turns out I told the world this in Vermont in 2017.  The following two slides showed these insights to the audience that day.  In 2024, I still do not think most of the world realizes the profound implications of these ideas.  The outside of our bodies uses light to control how we handle food.  This is when I realized food wasn't as important as I was taught to believe in medical school.  Light controls are far more critical than we all believe.  

In the video above, Jim mentioned the 1941 book, "What is Life". Schrödinger wrote in that book that he believed the heredity material is likely to be a molecule, which unlike a crystal does not repeat itself. He calls this an "aperiodic crystal".  That was written 13 years before DNA was discovered in 1953.  

An aperiodic crystal is a crystal that posses long range order and symmetry. The main property of crystal structure is its periodicity. This periodicity is due to the arrangement of atoms/molecules in the lattice points. The crystal structure as a whole can be considered as the repetition of unit cell.

Why is this a big deal?  

Each DNA strand holds dazzling possibilities for biology. When you play with a number of variables the environment can dish out to cells— the molecular make-up of water that surrounds it, the composition of the saline solution that holds it, and even the temperature of the room—can impact what the crystal of DNA looks like.  This ability fortells us it is a quantum computer.  There are many other shapes and forms to be found with DNA and the environment.  It is almost like the Library of Alexandria for life. How will this make a bigger impact on your perspective?  In a lab you can put hydrated DNA in a test tube and just vary the light and see what DNA is capable of in its crystalline form.  When you combine DNA with the variety of optical lighting settings within the microscope, and there are almost endless combinations to be explored in this molecule of life.  Aperiodic crystals exhibit many quantum abilities with respect to light.  Time restrictive feeding is one of those things.  

Time-restrictive feeding can induce shifts in the clock phase but does not alter the phase of DNA synthesis.  DNA is an aperiodic time crystal.   DNA crystals form when a double helix is suspended in a liquid that evaporates. They grow in patterns dictated by the information stored within the strands. When seen in cross-polarized light, they display a mind-bending kaleidoscope of color and shape. The vast range of crystal structures in DNA is impressive. (pic below)

WHY DO I ADVOCATE FOR THE BIG ASS BREAKFAST?  

That part of the Leptin Rx is also not about food.  It is about light.  I found a way to alter skin biology to allow it to perform some trickery with light.  Time-restrictive feeding alters diurnal sensitivity to UVB-induced DNA damage and expression of the critical DNA repair gene, Xpa.  In 2005, I found that when we eat is more important than what we eat.  Then, in 2017, centralized scientists gave me the data to prove my insights were correct in mice.    I shared them with my audience in my Vermont 2017 talk.   New data indicated that regulating skin function by feeding time in mammals emphasizes a link between circadian rhythm, food intake, and skin health.  

They had my TED talk in Nashville banned 15 years ago because Big Pharma knew the GLP-1 peptide drugs were in the pipeline for the obesity crisis.  They did not want the truth out about the leptin melanocortin pathway and how sunlight and cold work on it.  

The lies of Big Pharma's authority are more contagious than any virus, stickier than tar, and will die like a Kraken.  I know my enemies well in this battle.  

SUMMARY

Mammal skin provides the first line of defense against many environmental and stress factors for mammals that exhibit dramatic diurnal variations such as solar ultraviolet (UV) radiation and temperature.  Mammalian skin biology provides opportunities for the decentralized clinician to interrogate the clock regulation of tissue metabolism in the context of stem cells and regeneration with these insights.  In fact, mammal skin is most sensitive to UVB-induced damage at night, when expression of Xpa is lowest.  We can alter this with red light therapy and time restrictive feeding built into the Leptin Rx.  Melanin renovation further limits this damage.  The Leptin Rx and the melanin renovation Rx is antihetical to the Big Pharma paradigm in power now.  

The centralized medical system insists that they don’t know what causes many medical conditions and therefore they have no known cure. They discourage everyone from seeking a cure until Big Pharma finds the solution that they can take advantage of. They contradict and smear the reputation of anyone who is daring to find any treatment that is not part of their system. The only thing they offer those with mental illnesses is psychiatric medications, which in some cases might make life easier for caregivers, but does not help anyone recover from these illnesses. 

Centralized clinicians learn the art of self-delusion in their training.  They convince themselves that we are not letting patients down with the evidence based advice we were spoon fed, because we are doing the "clinically appropriate thing". Well-meant initiatives in centralized healthcare become misappropriated to justify neglect.  My writing seems to be my personal ipecac, but it makes me feel much better afterward, but sometimes people don’t like the result.

CITES

1. Adamovich Y., Rousso-Noori L., Zwighaft Z.,  Neufeld-Cohen A., Golik M., Kraut-Cohen J., Wang M., Han X., Asher G.  Circadian clocks and feeding time regulate the oscillations and levels of hepatic triglycerides.  Cell Metab. 2014; 19: 319-330

2. Damiola F., Le Minh N., Preitner N., Kornmann B., Fleury-Olela F., Schibler U.  Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus.  Genes Dev. 2000; 14: 2950-2961

3. Kuroda H. et al.  Meal frequency patterns determine the phase of mouse peripheral circadian clocks. Sci. Rep. 2012; 2: 711

4. Stokkan K.A. et al.  Entrainment of the circadian clock in the liver by feeding.  Science. 2001; 291: 490-493