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Dr. Jack Kruse
Dr. Jack Kruse

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HOW DOES TRANSGENERATIONAL EPIGENETICS CREATE DISEASE VIA POMC?



QUESTION: We have a type 1 diabetic daughter in our home, she is 11 and was diagnosed at 8. Type 1 is where your pancreas stops making insulin, not where you need to eat better, though low carb is a good idea for type 1 as well, so you don't have to pump so much insulin into the body... We go to regular checkups for her with the MD. I know they mean well. But, one of her cholesterol numbers is running high and they want us to reduce saturated fat. They mention the possibility of statin if we can't get the numbers down. NO THANKS. Her HDL and triglycerides are in good shape, but her LDL is high. Will sun exposure help this? Any other ideas?

She was diagnosed at age 8... The doctors just think it was some kind of illness that proceeded it, and that may be. Autoimmune issues also run in the family. I was diagnosed with Juvenile Rheumatoid arthritis at age 12. I was told I'd be in a wheelchair by age 40. Long story, I did some alternative things and was a lot better and lived with mild symptoms until the mid-'30s, kept experimenting, and got even better. Her weight is pretty good... just the LDL is high. But we can do better with carbs with her. In my reading, I have learned that some studies show that all of the vaccinations have something to do with a potential cause. Though we can't point to a timeline in her case, I think there may be something to that too.

ANSWER: Silencing the VDR enhances mitochondrial respiration and this is why obesity, diabetes, and cancer are all linked. What is the link? A lack of sunlight from 290-320nm silences the mitochondrial VDR. Type 1 came from mom transgenerationally having little to no solar exposure and she reprogrammed the egg you became. How do I know? The neuroprotective effect of vitamin D is associated with its influence on neurotrophin in the CNS production and release during POMC neurulation, neuromodulator synthesis, intracellular calcium homeostasis, and prevention of oxidative damage to nervous tissue(DHA protection = elovanoid protection in the egg). Your Mom likely had Neither to get type 1 DM. 


Clinical studies suggest that vit D deficiency may lead to an increased risk of future diseases of the CNS in offspring, particularly schizophrenia, multiple sclerosis, and diabetes. Adequate solar exposure of Mom is critical during pregnancy and for the child in the neonatal period seems to be crucial prevention of these diseases. If Mom never went out pre-pregnancy or during pregnancy, chances are brutally high that the baby never sees the sun either. Neurulation is the job of the thalamus in utero and this is where neurotrophin acts. Vitamin D makes neurotrophin in the CNS in utero. It is loaded with POMC and the VDR so our wide band gap semiconductors create biophotons 290-320 to make melanin and D3 = Vit D deficiency significantly affect brain cell differentiation/proliferation during the neonatal period. 


Since this post is about type 1 diabetes let's review a slide to see how blue light exposure from humans could affect a child who is not even born yet.  Recall in human females, they are born with all their oocytes. So those eggs are heavily programmed by her mother and her grandmother.  Evolution built the system this way so only the best eggs would be selected in new mothers by the leptin melanocortin pathways in the mother that are controlled by POMC.  Yes, Mom, leptin controls fecundity in HUMAN MAMMALS.  


Dad's gametes, called sperm don't show up in his testicles until puberty.  So what Dad's do from puberty to conception is quite important to the future child's construction plan too.  This is codified in methylation patterns and histone modification of chromatin as the video above shows.  So Mom and Dad........how doe slight from your childhoom ultimate effect the beta cells in your future child who isn't even born yet?  Carefully review the slide.  



Blue light or nnEMF exposure via the eye or skin ruin the programming of your clock genes and your skin controls the clock genes in your own gut.  Since women have their eggs fully ready to be programmed at birth this means her light exposure could ruins the clock genes in every egg in her ovary before she has ever thought about sex once in her life.  


Can ladies repiar this problem in their kids post natally when they are young?  

Yes.  If a parent knows they have this risk because a previous birth ended in a jaundiced baby or with a scar from a C section this blog is your wake up call.  Getting very tan and embracing light is key.  If you are a parent who has already made this error your job is to get your young infant/kid out in the sun without any sunscreen.  Yes, I know your flipping out now and your pediatrician is going nuts but they are not the smart tool in the tool box or the following would not be true.  

See the centralized guys do not know what they do not know and when what you do not know turns out to be the most important thing in disease risk...........well this is how unintended consequences happen.  

VIDEO  


Oh, don't think I haven't been warning the masses. they just ignored me because well I am a quack according to the centralized paradigm based in biochemistry understanding supported by Big Pharma.    

1. https://www.linkedin.com/pulse/your-baby-blue-light-jack-kruse/

2. https://www.linkedin.com/pulse/you-entangled-your-kid-via-morning-sickness-jack-kruse/

This is why autism, diabetes, obesity, and mental disease is exploding in our manufactured world that MOTHERS inhabit and they feel the need to be plugged into a grid to live instead of the sun. We've built a prison of poisonous light and the proof is seen in the last 5 generations of kids who are forming the next hominids via regressive evolution.




Big Pharma cannot patent the sun so they hide the truth from the masses of obedient idiots they call customers.



Of course, Big Pharma wants your daughter on a statin. It creates more future revenue streams.





Time to wake up. You’re getting played. That child needs the sun every day all day until diabetes goes away.  Oh, you think this is hyperboles.  Let's look what decentralized medicine data says below.



SUMMARY


You said, "She was diagnosed at age 8... The doctors just think it was some kind of illness that proceeded it, and that may be. Autoimmune issues also run in the family. I was diagnosed with Juvenile Rheumatoid arthritis at age 12. I was told I'd be in a wheelchair by age 40. Long story, I did some alternative things and was a lot better and lived with mild symptoms until the mid-'30s, kept experimenting, and got even better. Her weight is pretty good... just the LDL is high. But we can do better with carbs with her. In my reading, I have learned that some studies show that all of the vaccinations have something to do with a potential cause."  


REPLY: EVERY SINGLE ONE OF THESE FACTORS avove IS a mitochondrial toxin to redox power = REALITY CHECK: why they are all linked to a deep lack of UV light in that family,.......Mommy and Daddy's germ lines had the poison pill in them before the child was even created by your gamete union.  

That union is what created the heteroplasmic egg and voila......we got a type 1 kid.  The childs heteroplasmy rate in the beta cells of the pancreas were already high and that is why the child got diabetic so early in life.  The POMC defect was in her beta cells as soon as you guys got finished having sex.  


  It all fits  How did Mom & Dad screw the pooch initially? 


Vitamin A is linked to all the opsins in the brain as chromophores.    Vitamin D is linked to the skin.    Each Vitamin is entangled with one another because of its connection to the neuroectoderm in the embryo.    If there is a problem in the brain with Vitamin A due to the opsin problem say blue light toxicity or nnEMF exposure no matter if you are naked at the equator you won't make D3 from cholesterol because of this connection. The same connection can be found at the RXR receptor where both act.  That is how transgenerational epigenetics works in humans.  How can parents bad semiconductive like program an egg to create a disease that should not be here, but is now?  

The lipid rafts in humans is dominated by DHA, marine chain fish oil.  No, the answer is not pills.  It is seafood.  It is loaded with electrons that you need to capture sunlight.  Melanin is the photoreceptor in us that CREATES the most electrons in our bodies.  

DHA is the semiconductive fat that is the copper wire in the system but acts like a neurosurgeon when the system is stresed by oxidative damage of any type. 

What does it do?  

Note the photoreceptor destruction issues mentioned in the top line of the slide.  There are hundred of them destroyed besides melanopsin when this occurs in the egg of a women from the time she is born until she gives birth.  Melanin is one of the photoreceptors this slide is referencing with.  This mean a woman who tans regularly before she has choildren is optimizing her future childs life.  

So things that protect photorecepetors are all part of the melanin renovation program for ANY CHILD.  Not surprisingly, docosahexaenoic acid (DHA) is a big help in renovating all photoreceptors in mammals. How?   DHA is broken down into elovanoids under any stressor.  Elovanoids (ELVs) enhance expression of pro-survival proteins in cells undergoing uncompensated oxidative stress.  No other omega 3 has this ability.  This is why evolution has not replaced it once in 650 million years of evolutionary history on EARTH.  Let that sink in.  DHA helps stimulate autophagy to recycle photoreceptors in mammals.  We have the most DHA in our tissues as a mammal for a reason; our brain is unique in the mammalian family.  DHA also fills the human oocyte.  

Oh.........Happy Mother's Day.  

I hope all you Mother's realize how we work and why kids are the way they are.  Because we programmed their egg with our decisions around light.  Change that before you decide to become a parent.  It will save a lot of heartache.  


CITES: 


My cerebral cortex

HOW DOES TRANSGENERATIONAL EPIGENETICS CREATE DISEASE VIA POMC?

Comments

Yes, epigenetics is real and powerful. Dr. Bianca Jones Marlin (The Marlin Lab) is studying epigenetics. She looked at a famine in The Netherlands ("Dutch Hunger Winter") which lasted for a very short period of time in the 1940's, but the future generations developed diabetes, etc. As an African-American, it infuriates me to think of the trauma that my forebears endured during chattel slavery, let alone the "continued" trauma, terror, and et cetera afterwards. People blame the higher numbers of HBP amongst African-Americans on diet when I believe it's clearly epigenetics at play. When you enter perimenopause and your adrenal glands become responsible for hormone production, it becomes clear who has stress in their lives. Some people's lives are a literal shock experiment, and the damage started generations ago.

Lashawn Hill

We have a family that all have ALS -like symptoms… but Iam 99% certain that it isn’t kuru. We don’t have many cannibals left now, and the cannibals are all in a different clan.

Christopher Jones

The sun here is very intense… 3-4 degrees south of the equator. We live in a swamp in the sepik basin. Diet is consistently sago starch, river fish, greens, and occasional pig or cassowary or other small game. Some other seasonal or cultivated fruits… mango, papaya, coconut… and whatever flooding doesn’t destroy in their gardens ( squash, corn, sweet potatoes, tapioc, yam, banana) Tons of malaria, random weird fevers and cold-like symptoms. Lots of tropical ulcers and boils. We have a lot of cataracts in older people. Are darker-skinned people more sensitive to ‘lack of sun exposure’? The heat and solar intensity cause everyone to work and relax in the shade as often as possible. It is really really humid all the time, and can get up to 100 degrees. None of us have glass windows. I feel like after a lot of sun exposure, the bugs ‘like me more’, but I probably sleep better and am less depressed!

Christopher Jones

I live in a tribe of hunters and gatherers in PNG. Plenty of sun (though I have some questions about that!) We still have high incidence of plenty of sickness and disease… there are even a few fat people. Nearly all of our diet is totally local… we drink river and rain water… Most people are really really lean. Younger ones occasionally put on a good amount of lean tissue… a few really jacked looking guys, and peeled. My eyeball dexa scan would put many of the men at sub 10% . My eyeball dexa isn’t too good at women tho. Most of our young girls go through puberty starting as early as 10!(nobody really knows how old they are here… but we moved in ~13 years ago, and can track well enough against that) Trying to figure this all out. I’m a noob and not a medical professional… any explanations?

Christopher Jones

The Pottenger cat study is a great example of inheriting disease from parents via malnutrition. i.e. biological weakness.

Warren

Your words of encouragement for your son Konnor are really thought provocative and I find the very idea of your jotting them down for posterity really educational for me as a father of one son in his 20's. He asked me to write a book for him with the most pertinent aspects for health, wealth, and wise living. When he asked me that question, I took a moment to wonder "what shall I write" for him to use as a sort of reference book to utilize in helping to guide his life. Your words reflect what my son and I have come to realize just speaking today. He asked about this so called "book" some three years ago. Today, we agreed upon the one fact that is most important in passing on so called advice. He must go forward and write his own book trusting in his own skills and imagination; not follow teachings of mine, as much as I used to think I had to make life easier for him. So too likewise, I must forge ahead with the life I must create through my imagination, awareness and skills. What has happened for me in these last three years is rather spectacular. Even though we are about 1,000 miles apart from one another, our day-to-day interactions on the brief use of cell phones, has brought us both closer to each other. He shares with me the passionate aspects of his dreams and present goals with accomplishments and or shortcomings, and I relate the same to him. The active participation is the story book that we both are crafting together. Our conversations about the realm of mitochondria behaviors are in its infancy. However, he has added one more aspect to his day, with the surprising aspect of adding sunlight to his normal wellness protocol, every day. He has heard me reference the name of a unique family doctor (the Kruseman), I utilize for helping me establish my own wellness protocol. I do agree with your closing sentences, "but love is never enough in this kind of journey". So true, so real, and completely, in your face. Life is so, so real, it demands your unconditional "all in" on every level. The choice is now much clearer for me as a father and a human being on earth. I can choose to go and watch the football game as a spectator in the stands with little commitment and hardly and involvement; or I can choose the be the quarterback in the game on the field of life, calling the shots and the plays, as a fully vested and committed participant. When life becomes that spectator sport, rather than that participatory endeavor, all of what might have been is completely passed by and lost forever. The kind words you drafted to your son, helped me see that reality, on this milestone of a day.

michael john moreau

Thanks again Jack. Yes, I said that to my contact when I first heard about this - I was wondering if there is anything else that could be done. But I have passed this on and hope that her Mum is able and willing to put a plan of action into place.

Enid Ginn

the same as always. Allow natural full spectrum sunlight that contain 380nm light into her eye.

Dr. Jack Kruse

Hi Jack - I have another question for you and hope you can point out the right direction. I know of a little girl, perhaps 2 years old, who has just been diagnosed with retinal cancer. Given the information in your post, I see that there may be a lack of sun exposure by Mom during pregnancy. Do you have any recommendations I can pass along that might help this darling little girl? Many thanks!

Enid Ginn

May 14, 2016 was the day my son graduated as an engineer. So today has a lot of meaning. I wrote this to him that day.Today is college graduation day and I have a lot on my mind this AM: The card I got you did not have enough room to say to you what I needed to say today. So you think you've finished with your education KSK1? That is so far from the truth you're about to embark on. Life is going to teach you a lot more than a pile of facts. Here is some fatherly advice: don’t let the noise of other’s opinions drown out your opinion. Extraordinary beautiful paths can't be discovered without getting lost for a time in your journey. Never let critics dull your shine. You get to consciously decide what has meaning and what doesn’t in your life. Those who tell you who and what to worship should be subtracted from your life. If they are related to you, eradicate them with more zest. You get to decide what to worship now. The real tests await your actions in these matters. The journey of life is amazingly beautiful if you take it as a fearless adventure. Create your own dogma based on your own experiences and wisdom. That dogma will morph into your own unique art. Early on it will be an art show few will come to appreciate, but in time when you build it with a strong foundation, they will come. From my point of view, I graduated with science degrees and all this nonsense tied to surgery, I had no idea what I was going to create back then. When I realized I created havoc unintentionally, more harm than good really, it was then when I became wise. My failures taught me what I "should work" to create for others. It was at odds with what I was taught. Develop a passion for developing your ideas, "your art". If you do, you will never cease to grow, and that growth can help mankind. When I finished my residency in neurosurgery I found out I was more of a storyteller. I was peddling a story of someone else's truth, and not the innate truth nature built into man. That let the air out of my passion. I was lucky because my failures got me focused on what I was missing. Just because you fail does not mean you cannot reclaim your passion. Start out today, as you walk across that stage with a new perspective that your shortcomings will guide you well. See your life as something artful, a new creation that the world is not ready for. Too many young people just wait around waiting to be told what to make with their life instead of making others ready for their art. Your life and your work should be distinct from the crowd you graduating with today. The wise never confuse the two. The second is a small part of the first. College treats you like you are a pack animal. A single number in a sea of numerals. The only safe position in a pack is in the lead. College does not teach you how to lead. Leaders live by choice, not by accident, not by what is contained in books. If you're not passionate enough from the start, you'll never stick it out. Businesses, design teams, your employers, and your colleagues, are looking to throw you to the wolves and see who returns leading the pack; they are not interested in a crowd with echoes for ideas. Education provides you with guidance, but it is not a true teacher. There is no script in life. It must live and be executed with abandon. Imbibe its lessons. Your happiness and success are the measure of how you'll fare on that test. I remember going to my last graduation thinking to myself as I walked across the stage what bullshit the entire process was. It pissed off my family and those there, but I knew better. I realized the old rules in my profession were already crumbling and nobody had a damn clue what the new rules would be.....I decided that day to make up my own rules of engagement and be who I thought we needed and not fulfill what they taught me to be. Be unique son. If you want something new out of this life, you have to stop doing what old guys do and believe is right. It's OK to be scared to fail. Vulnerability is the birthplace of innovation, creativity, and change. Today when I see you walk across that stage, I want you to reflect on my words as something meaningful, powerful, and true. Something no one ever told me when I was beginning my life after being schooled: In a world in desperate need of change, the "learners" shall inherit the earth, while the learned shall find themselves perfectly suited for a world that no longer exists. What you just learned needs to be buried. They only admit this during the speech they pay some other guy to give to you. Some call it ironic, but I think it is the first true thing education gives a new graduate. Focus on what you don't know yet, and not on what you think you know. Focus on your deficits, and do so without arrogance. When you remain curious you'll be asked questions no one thought to ask and you'll be the first person to provide uncommon ideas that work. You'll realize what few do........Ordinary people believe only in the possible because of what they learned. They take those lessons as gospel. Extraordinary people visualize not what is possible or probable, but rather what is completely impossible and unfathomable to most. And by visualizing the impossible, you'll begin to see things manifest as possible in your life to change the world. The difference between ordinary and extraordinary is that little extra. Do not settle, just because you're graduating. Formal education and your current position within your class can define your worthiness today. It does nothing for your future. What makes you extraordinary is defined by your attitude toward the life you're getting ready to live and how you treat others. You've been given the gift of talent, but you were never promised success, much less happiness. So many you'll graduate with today do not have this concept down. Their too drunk off their successes when they will need to gain wisdom from the many failures they now face. Your talent has to meet its potential in this life. Potential pays no dividends. Ineffective people live day after day with unused potential. If you want to be great you have to let it all hang out and take risks. Safety nets are what your parents gave you for the first 22 years of your life...............but what you are about to embark on has no nets or safety. It is reality. It isn't where or who you came from; it's where you're going that counts. Vision is tomorrow's reality expressed as an idea today. As an engineer, if you do not have good ideas every day, you're not focused on the correct prize. Potential, like ideas, have a shelf life. Ideation without execution leads to the deletion of your ideas and shrinks your potential. Our lives are mere flashes of light in an infinitely empty universe. In the 2 decades of education I endured, the most important lesson I received from the experience was that what we observe as “normal” living is truly a travesty of our potential. In a society so governed by superficiality, appearances, and petty economics, dreams are more real than anything in the “real world”. Our imagination is where we engineer our best plans. You must refuse normalcy and take the paths few will. If not you, who will? Beauty is everywhere in nature Konnor, love is endless there, and joy bleeds from our everyday existence. Embrace it, don't run from it, as I did for 4 decades. For 22 years you've been in rehearsal, today is just the dress rehearsal, and soon the play will go live with paying customers who have expectations of a great performance from you. Your ability and choices will then be on display for the world to see and judge. Sandy and I love you, but love is never enough in this kind of journey. The journey is not over today.........it just got real when the tassel hits the other side.

Dr. Jack Kruse

FAKE NEWS IS A BUSINESS. FAKE CENTRALIZED SCIENCE has become the most PROFITABLE version of manufactured truth for the profiteers.

Dr. Jack Kruse

In 2006 I gave birth to a baby boy by c-section that was premature and had a birth defect on the severe side. I was told this wasn’t my fault but honestly it made the shame worse. I had one kind doctor told me he thought he had to do with the water. I had no idea until a couple of years ago he was talking about my water. I’ve been looking at a hair on an elephant. Every year we go to his specialist surgeon, more and more boys are in that waiting room. I want to throw up because it is those little souls that are subject to the consequences. This post makes my heart sing. This is where the hope lives and breathes.

Stefanie Green


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