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Dr. Jack Kruse
Dr. Jack Kruse

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QUANTUM ENGINEERING #39: MELANIN CONTROLS EVOLUTIONARY TRAJECTORY IN MAMMALS

The "regressive evolution" of living a species on Earth has spawned interesting new ideas in new species.  The most interesting regression to me is now seen in humans on social media.  It is hiding right in plain sight and you can only see it if you maintain the wide band gapped semiconductors in your brain.  Improving them in your body no longer is operational.  Darwin is attributed to the quote that survival is linked to the survival of the fittest, but 20 years ago I realized his perspective was myopic.  I believe it should now be about the survival of the wisest.    INTELLECT IS NOT WISDOM.

Only wise humans who can see the loss of human superpower happening at breakneck speed will survive this "backward evolution".  Wisdom for today's mammals is born inside their melanin sheets inside their skulls.  Wisdom makes you the most adaptable creature in a rapidly changing environment.  What is changing fast?  Light is.

Light is the creative "Source" in the universe.  To some "backward evolution" may imply a loss of complexity, misleading you to believe, that evolution has a goal of creating more complex forms. It doesn't However, evolution merely favors features that make a poster "more fit" for a particular current environment.

Consider cave-dwelling fish in Mexico below.

Look at the fish.  Implications of the picture?  What you do isn't what you think. Let me explain the creative process buried at the core of life.  The evolutionary process doesn't retrace its steps in "regressive evolution".  It just appears it to those who do not carefully observe the process.  You have to go deeper than the facade.  Cave-dwelling creatures have frequently undergone "regressive evolution",  due to their unique light environment.  Remember fish are not mammals, but they have lessons for mammals to learn.  These fish have lost many complex features, like eyes, that are not needed in dark environments. But eye loss in cavefish, for example, doesn't mean an exact return to a primordial ancestor without these organs. The eye remnants remain.  They are atrophic and lie in wait until the light, the "Source code" returns.  Instead, processes that previously produced the eye stop partway through the process, leaving a vestigial eye overgrown with skin.

I believe the same process occurred in the primate clade of mammals in Africa 2-4 million years ago to explain our species.

To a surface thinker with low dopamine, due to degraded melanin sheets in their skulls, things can look like they're going into reverse when they aren't. The eye didn't go in reverse. It just stopped going forward.  Might humans represent the same thing in the chimp family?

Might it even be more complex today compared to our own genesis?

I believe this is exactly what is happening to human mammals today.  They are no longer moving forward, and their epigenetic toolbox which relies on UV light to drive mitosis, is also regressing.  What does that imply?  The cavefish doesn't face this now because it is not a mammal and it is protected fully from man's use of artificial light.

What is happening to mammals that aren't in Nature and are subject to man made light?

That is how it looks on the primate side who doesn't talk, how does it look in their cousins who can speak?

What was perfection 520 years ago in stone?

As humans have degraded the melanin sheets inside their skulls with the use of clothing and indoor dwelling with fire use they have become more creative.  Creativity is a regressive evolutionary creation in my opinion of regressive changes in the frontal lobes.  This regressive change has had a positive connotation which can be seen in the Louve in Paris.  Melanin degradations created various levels of dopamine in our frontal lobes that lead to new things on Earth.  There is a lesson here.

Losses in biological complexity may accompany less-obvious increases in complexity in other areas of humanity.  This manifests in novel ways, such as the biochemistries parasites use to get inside hosts and sculpt changes in us by changing light frequencies in our cells.  How big a deal is this?  Men's face change due to toxoplasmosis.

The sex of offspring change when women infected get pregnant.  What happens to the mitochondrial DNA of women with POMC deficiency over several generations since they control mtDNA inheritance.  Do you understand what "regressive evolution" really means?    I think autism is the first step in new speciation.

It's very easy for people who do not understand science to think of evolution in terms of what you see; what the morphological features are in living things. But there are also lots of other features that we don't perceive at the physiological and the biochemical level.  It turns out POMC is working at the biophysical level.  This is well below the classic world of reality.  It is well hidden by Nature.

In cavefish, lost eyes may similarly obscure alternative complexity. Organs responsive to vibrations appear in great quantities in these fish, providing another way to sense in dark environments. And in the already-overstuffed head, these organs found available real estate in the fish's empty eye sockets.  Nature is efficient in how she operates even in regression.

When Alan Turing turned his mind to biology in 1952, he proposed a model for how biological patterns could stem from the interaction of just two molecules. New work hints that it’s what all vertebrates use to grow hair, feathers, and other skin structures that links to melanin biology.


In 1952, well before developmental biologists spoke in terms of Hox genes and transcription factors, or even understood DNA’s structure, Alan Turing had an heretical idea.

Turing wanted to understand the underlying mechanism that produces natural patterns. He proposed that patterns such as spots form as a result of the interactions between two chemicals that spread throughout a system much like gas atoms in a box do, with one crucial difference. Instead of diffusing evenly like a gas, the chemicals, which Turing called “morphogens,” diffuse at different rates. One serves as an activator to express a unique characteristic, like a tiger’s stripe, and the other acts as an inhibitor, kicking in periodically to shut down the activator’s expression.

How would this work?

Imagine a field of dry grass dotted with grasshoppers. If the grass were set on fire at several random points and no moisture were present to inhibit the flames.  The fires would char the entire field. If this scenario played out like a Turing mechanism, however, the heat from the encroaching flames would cause some of the fleeing grasshoppers to sweat, dampening the grass around them and thereby creating periodic unburned spots in the otherwise burned field.  A pattern would develop.  POMC operates the same way on the body plan genes to sculpt us.  This is where our new frontal lobes in the brain came from and where bipedalism came from.  It also explains why POMC is heavily expressed in our skin overlying our gut that shortened by 30 feet from our cousins.

Some centralized biologists remain skeptical that Turing mechanisms are sufficient to account for these periodic patterns, particularly because there are other viable models, including one proposed by Lewis Wolpert, an emeritus developmental biologist at University College London. In Wolpert’s model, cells interpret their position in space based on how much of each morphogen there is, resulting in stripes, spots or digits. Furthermore, Wolpert says, “no one has yet identified the molecules that work for a Turing mechanism in development.”

Uncle Jack thinks alpha MSH and ACTH/blood glucose are the morphogen and activator in the Turing mechanism of mammals and UV light from our environment and inside of our bodies powers the process of building the mammalian body plan to explain morphogensis.

Centralized biology ignored this paper for decades after Turing's death.  Only mathematicians toyed with it.  In my 18 months of unlearning to relearn, I realized what Turing found.  He found a way to allow mathematics to bridge the gap between reality to the quantum world.  How?

POMC is a gene made out of atoms.  Since the beginning of the universe, we know one thing for sure.  There were quantum subatomic particles present at genesis.  First and foremost, this implies that a quantum evolution began as a by-product of some type of supernova blast.  All atoms come from these blasts.  This quantum mechanism evolved into a chemical evolution with the construction of atoms.  From this chemical evolution emerged biochemical evolution directed by light some 3.8 billion years ago.  No one is following these clues back to how all things began except Turing.  It is all linked to H+/D binary code.

Atoms are in everything that makes us, especially proteins which come from genes like POMC.  Every part of you is made up by atoms right now.  All atoms are controlled by light at some level = they are quantized.  The laws of the universe scale from the quantum level to the macroscopic level.  Quantum mechanics is foundational to everything in this universe.  This implies that, in order to have a fundamental understanding of life, you must have a quantized molecular mechanism to prove your theory.

Darwin has nothing to prove anything with what he wrote in the Origin of Species. He provided us with observations that correlated to morphologic change.  This was correlative data, not causative data.  Lots of people forget that basic fault because of guys like Huxley and Dawkins.

When you are dealing with atoms, you are dealing with quantum mechanics.  This is an area where Dawkins will have to trick you to believe Darwin’s ideas.  Nothing in Darwin’s theory talks about nature’s basic quantum language because it was not discovered yet.  Darwin gets a pass on that but Dawkins does not from me.  Feynman famously said that if your theory does not match your experiment, no matter how elegant the theory,  it is wrong.  Well, I am going to show you Darwin was, in fact, wrong.  I am going to use quantum mechanics to show you why.  The key to understanding how evolution occurs is to understand the fundamentals of Einstein’s mass equivalence equation E =mc^2.

The mass equivalence equation shows us the wide reaching impacts of failing to understand how small changes in quantum mass can create widespread changes in energy.  How does math scale to the quantum world?   Avogadro’s constant is the only scaling factor we have that allows us to go between the macroscopic world to the quantum level (sub atomic scale).  This allows us to link observations we make in nature, with respect to atoms, directly to the mathematics of the quantum realm.

You heard me mention this relationship in the podcast I did with Max Gulhane, MD from Australia and Sarah Pugh of the UK when I talked about how much water is created from fats and carbohydrates and I mentioned that fats created double the amount of moles of water than sugar does.  This means more H+ is harvested in fats than carbohydrates.  One mole of a substance is equal to 6.022 × 10²³ units of that substance (such as atoms, molecules, or ions). The number 6.022 × 10²³ is known as Avogadro's constant.


Just from common sense, quantum mechanics describes nature as absurd.  Then the quantum experiments have validated nature’s absurd behavior, we must accept Lady Evolution as she is; bizarre and  absurd.   QED seems counterintuitive to evolutionary biology because she asks you to read the mass equivalence equation right to left in order to understand her.  Life is fundamentally a thermodynamic problem to solve, not an evolutionary one.  E=mc^2 means that 2 x3 = 6 just like 3 x 2 = 6.  Few realize that is built into Einstein’s mass equivalence equation.

The key for quantum evolution is to know how the molecules of life, namely proteins, change over time.  Subatomic particles change the charge and change the size and shape of molecules and this leads to new emergent properties macroscopically in animals.  POMC is the mammalian gene that introduced charge variation and size and shape changes to proteins to cause them to act differently.

Biological diversity, across the board, is based on a fairly restricted set of principles that seem to work and are reused over and over again in evolution.  This seems especially true in the evolution or mammals and therapod dinosaurs/birds over the last 65 million years. Nature, in all its exuberant inventiveness, may be more conservative than we thought in creating changes in morphology.

SUMMARY

Part of the reason evolution doesn't retrace its steps is that adaptations lead to other changes. That makes simply dialing back a specific change extremely complicated.

If you've made a change, you're going to fine-tune that adaptation, and that adaptation will have to interact with other genes to sculpt out a solution with staying power.  Now, if you reverse that one change, all of the other genes are still going to have to be changed to reverse evolution.

In cavefish, for example, the original development of an eye may have come with changes not only to the semiconductive proteins needed for eyes but also to skull structures of an eye socket. A mutation affecting an eye protein wouldn't cause an organism to revert to one without the socket.

Changes in the the environment always predates changes in the semiconductive fab plants in cells.  When thought of in this way, you can see why Nature never makes mistakes. Evolution is always progressive in that it's selecting for features that improve the fitness of the individuals in which that variation is being expressed.

If DNA genes matter so much why is it that most, not all, circadian gene regulation occurs at a post transcriptional time frame?  Post-transcriptional regulation is the control of gene expression at the RNA level. It occurs AFTER the RNA polymerase has been attached to the gene's promoter and is synthesizing the nucleotide sequence. This means the gene is not the key to change.  It means the process after gene expression are the key to how wide band gapped semiconductors in you sculpt tissues.  Therefore, as the name indicates, it occurs between the transcription phase and the translation phase of gene expression.

These controls are critical for the regulation of many genes across human tissues. It also plays a huge role in cell physiology, being implicated in pathologies such as cancer and neurodegenerative diseases in humans.  This tells us that these diseases are caused by environmental changes and not GENETIC ones.  This is why I told Dr. Huberman and Rick Darwin was wrong in his approach and the neo Darwinists like Dawkins are really wrong.  I can give Darwin a pass because quantum mechanics was not discovered until 50 years after his penned his theory.  I cannot absolve Dawkins of this.  His self gene book was penned over 50 years from the discovery of quantum mechanics.   The implications for you care clear.  Centralized science still acts like Darwin was correct.  This makes no sense from a scientific point of view does it?  Darwin said small changes in genes called mutations leads to variation of species.  This is a huge problem for neo-Darwinians. Why?  A post transcriptional protein results in a non-functional protein for life.  Proteins must have all four bends to work properly in cells.  So how could life’s stage be gene based?

Life is like a photograph; it develops from the negatives in the environment.  What is next for humans on Earth?

I now believe creativity, and most mental diseases, are a regressive evolutionary creation in my opinion of regressive changes in the frontal lobes.  Many modern diseases are evidence of proteins undergoing semiconductive engineering inside your tissues to change the frequencies of light in your tissues.  This leads to new and alien bends, charges, and alteration of atoms in your tissues that change the morphology of your body and the physiology of your tissues.  The most powerful changes are occurring in the POMC gene family and all the peptides it creates by light frequency cleavage.

CITES

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3363033/

https://www.science.org/doi/10.1126/sciadv.aau5484

https://www.newscientist.com/article/mg25834344-900-the-shocking-decline-of-earths-microbiome-and-how-to-save-it/

QUANTUM ENGINEERING #39: MELANIN CONTROLS EVOLUTIONARY TRAJECTORY IN MAMMALS QUANTUM ENGINEERING #39: MELANIN CONTROLS EVOLUTIONARY TRAJECTORY IN MAMMALS QUANTUM ENGINEERING #39: MELANIN CONTROLS EVOLUTIONARY TRAJECTORY IN MAMMALS QUANTUM ENGINEERING #39: MELANIN CONTROLS EVOLUTIONARY TRAJECTORY IN MAMMALS QUANTUM ENGINEERING #39: MELANIN CONTROLS EVOLUTIONARY TRAJECTORY IN MAMMALS QUANTUM ENGINEERING #39: MELANIN CONTROLS EVOLUTIONARY TRAJECTORY IN MAMMALS

Comments

Uncle Jack, do you think when our brains shrunk inside those caves, that the artwork like in Lascaux could have been a way to offload the memory to preserve brain capacity ? Is art a reduction of natural experience to singular compressed expression ?

Max

Thanks!

Miquel

it is garbage.

Dr. Jack Kruse

I'm done toying with centralized science. You feel me yet? What I have learned about Public Health over my surgical career? Talk is cheap for politicians and epidemiologists. Since talk is cheap, then being silent is expensive for the public and for MDs. Most folks it seems, can't afford to buy into it. It is wise to be aware of people who are standing in your midst and who refuse to smile when you win. Make sure during this time you carefully reevaluate your own network of misfits. Check out my latest article: PUSHING A CANCELLED RESEARCHER TO THE FINISH LINE. https://www.linkedin.com/pulse/pushing-cancelled-researcher-finish-line-jack-kruse

Dr. Jack Kruse

Uncle Jack! How many time you think is needed to do a melanin renovation Rx? What do you think about topical use of tyrosine and alpha msh? It could help accelerate the process? I found some studies of grey hair reversion using that. I saw a medical doctor talking about melanin and human photosynthesis, and talking about a drug called QIAPI1 to restore our capacity to produce ligth, what a hell is that? Is that related to methylene blue?

Miquel

What do centralized healthcare providers need to know? History of their profession so they can make better adaptations for patients. If you listened to the Huberman/Rubin podcast I just did on Tetragrammaton you'll want more of the details that lead me to POMC and melanin. Here is the part of that story that EVERY MD needs to assimilate. I wrote this blog last night after doing a consult for a centralized MD. I hope it helps many of you. Check out my latest article: HOW I GOT ON THE POMC/MELANIN TRACK AFTER MY MICHELANGELO EUREKA? https://www.linkedin.com/pulse/how-i-got-pomcmelanin-track-after-my-michelangelo-eureka-jack-kruse

Dr. Jack Kruse

Hi Jack, wonderful post and connecting the dots (facts) on many levels for me. This is question for anyone in the tribe..Background first. I come from a family of 4 boys, all born in the spring time. Yes, my father fits the description in Jack's post perfectly. He was also a alpha male and very successful in life..ie, doors opened everywhere for him. We all have some sort of inherently defects..outlined by Jack's analysis. My mother albeit a model woman, blond and beautiful lived indoors, her pregnancies, gestational periods were during classic, summer-winter. In childhood she came from a poor family growing up in polluted city of Sydney, Australia during 1930's in a depression... if this makes any difference. Here is my enquiry following Jack's post...Does anyone know if most Males are born in spring time? And is there data for the likelihood of brain related condition, personality complexes or any incidence of cognitive or modern malaise....such as paranoia, or bipolar etc. My only observations are from family reunions..school playgrounds, working careers and parties. Many thanks, rgds Chris S

Chris Sussmilch

Part 2 of my podcast is now live with Mr. Rick Rubin, Dr. Andrew Huberman and myself. Have a listen. Agent provocateur's try to bring grit to arguments to create progress. I view myself as an agent provocateur for centralized science. Small grits of sand become gorgeous pearls with pressure or time in an oyster. To succeed at anything worthwhile in life requires persistence, no matter how gifted, fortunate, or passionate you are. Once the oyster finds that right grain of sand the artist begins. Creativity then manifests. This grit allowed my to pause the science of medicine and embrace the art of medicine that is buried in Nature's recipes for cells. Nature is our elixir vitae. Once you find your passion and your "pot," you need to hang in there--you need to persist. In a world, where reality says you cannot store the fruit of your labor across time, how can you establish a relationship that is predictable with the world to get ahead. Water does this for light and your cells take full advantage of this store of energy, information, and value. The "games" that nature plays on our cells is quite intricate. Uncovering them is my passion. Become comfortable with uncertainty. Uncertainity is part of thre fabric of Nature and she pulls on your threads via your cells using it. The great human error is thinking that there can be an antidote to the uncertainty in life. This is Mother Nature’s key credo of the mitochondriac. You will hear that passion in all three of us. Can you live with uncertainty? I want to live with doubt and embrace the uncertainty and not knowing. I think it is much more interesting to live not knowing than to have answers that might be wrong. Living life believing bullshit centralized lies and half-truths is a horrendous fate in life. Life isn’t meant to be lived perfectly because of certainty……Life merely needs to be LIVED. It should be sampled boldly, wildly, beautifully, uncertainty, imperfectly, but magically LIVED. Let go of certainty. The opposite isn't uncertainty. It's openness, curiosity and a willingness to embrace paradox, rather than choose up sides. The ultimate challenge is to accept ourselves exactly as we are, but never stop trying to learn and grow. You have to embrace the suck in life. Life develops from our negatives, our mistakes. When you listen to it, read the blogs on POMC/melanin, judge me below. For me, courage within a friendship becomes real when you know implicitly at the outset you're licked before commencement, but you start anyway and see things through no matter what because folks are counting on you in some small way. Sometimes, reaching out to another's mind is the beginning of a journey. At other times, touching their hand allows another to take your journey in the future when you are gone. Wisdom is the seed mammals need now. Not letting go is the bond I'm looking for in sharing my life's work. No person is your friend who demands your silence or denies your right to grow. https://podcasts.apple.com/gb/podcast/dr-jack-kruse-and-andrew-huberman-ph-d-part-2/id1671669052?i=1000611559742

Dr. Jack Kruse

read the sunscreen blog in this series about ten blogs ago. epic

Dr. Jack Kruse

Hi Doc. Listened to the podcast w Huberman today. Signed up for my Patreon sub immediately afterwards. Not sure if this is the right place to ask but I’m especially curious about your thoughts around squamous cell carcinoma after hearing you talk about melanoma. I had some removed two years ago and believe I’ve had it come back in another location. First time on my upper thigh (where the sun rarely shined) and now it’s reappeared on my mid back. I’m looking forward to the journey with you and appreciate you trying to connect with those of us who feel disenfranchised by the modern system but are unable to find the correct off ramp to the decentralized world. I’m prototypical in that I’ve tried and followed everyone (Wolff, Asprey, Attia, etc) you spoke of and am still searching as I haven’t found the bedrock yet. Keep up the good work, UJ.

Trent Brookshire

Here is the replay of today's live event for those who missed it. Are you wise about your life? Wisdom is the dictionary of common sense. Wisdom is living out our purpose with passion. Wisdom is knowing that if you're about to swing the bat you've made sure you're in the right ballpark. Wisdom is appointing yourself an expert at being yourself. Wisdom is knowing where, when, and how to make a difference in the lives of others. Nothing in the world is more dangerous than sincere ignorance and conscientious stupidity. Wisdom is applying the appropriate knowledge at the right time. We need the wisdom to lead, live and leave a legacy. Wisdom maintains relationships during stress, it is seen in attitudes of love, servanthood, and humility. Today become wise. Become discerning. Reflect on these things and watch your life grow. https://www.clubhouse.com/room/ME6JJn8l?utm_medium=ch_room_xr&utm_campaign=E4eIV-j7JuI-UnU51oZ0ow-700618

Dr. Jack Kruse

Uncles usually are more curious relatives too (: Thanks so much.

Roman S Shapoval

my curiosity.

Dr. Jack Kruse

I love how you say how creativity can be a regression. I was inspired to research melanin thanks to you Uncle Jack, and it showed me that Nature already built in that creativity for us, and now Nasa wants to back-engineer the same creativity because we're devolving off this planet. Thanks for sharing the video too. Other than the Sun, you're one of my main sources of info and inspiration, which I seek to translate and make understandable for my audience. May I ask, who was your main source when you had to unlearn everything? Did you have an Uncle Jack? Thanks so much.

Roman S Shapoval

That makes so much sense laid out like that. I had that thought about autism being a form of evolution and dismissed it because I didn’t understand it. Now I think I do. Fantastic writing Jack.

David Mc Gettigan


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