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Dr. Jack Kruse
Dr. Jack Kruse

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QUANTUM ENGINEERING #23: CIRCADIAN CLOCK MANAGEMENT

Good circadian clock management creates lives with less volume creation and more storage at night for urine. Nature seems to want diurnal mammals to drink water prior to sleep.  The system is built for this type of behavior.  All neurons move and release water when neurons fire action potentials. Thirst is controlled by posterior pituitary vasopressin.  Vasopressin is directly acted upon by light coming in through the central retinal pathways to affect the posterior pituitary.  The posterior pituitary output affects the immune system's ability to function.  The nervous and immune systems are engaged in bidirectional communication as the picture shows.  Vasopressin is a big part of this blueprint.

I believe all autoimmune diseases are related to the disruption of the bi-directional reflex loops you see in the pictures above.  I believe the damage begins with light we are not built for.

T-Cells are the key player in autoimmune conditions. We've known this since 2003. In 2016 we found out how blue light causes T-cell motility. We now have all the pieces to explain the basic mechanism of all autoimmune diseases and why it is linked to the blue hazard.  HYPERLINK

Autoreactive T lymphocytes are key players in autoimmune diseases. They can act both as regulatory and effector cells. Various animal models have been used in the literature to show that the transfer of autoreactive T cells is sufficient to induce a model of an autoimmune disease. Thus, the pathogenic importance of autoreactive T cells has been formally demonstrated in animals. This should inform centralized healthcare that autoimmunity is tied to our light choices but patients never get told this.

Robert O. Becker taught us that injured tissue elicited an electromagnetic signal to begin wound repair. He found that an electrostatic field, negative away from the limb stump, could enable the regeneration of a frog limb.  Becker ascribed regeneration capability to the existence of a nucleus in the salamander's erythrocyte. (The mature erythrocytes of frogs and higher animals lacked a nucleus.) Erythrocytes with nuclei seemed to have the dedifferentiation capability required for later differentiating into the various cell types needed in the growth area. Becker described these studies in his 1985 book The Body Electric, and also (condensed and compared with other fields) in the first part of his 1990 book Cross Currents.

The video above also shows this effect in the animal modeling of human cell injury in trauma.

Vasopressin (AVP) is released after every type of brain injury.  All injuries cause an electromagnetic stimulus to direct repair, as Becker found in his work.  This tells us vasopressin responds to electromagnetic stimuli even outside its normal circadian cycle.  Non-terrestrial forms of light is a light stress.  It is a form of traumatic brain injury.  Light injuries have become the most common non-military injury humans get in the modern world in their neurons.

Normally vasopressin is released at night when light is not present.  Artificial light post-sunset causes massive early chronic release of vasopressin.  Screen time during the day exacerbates this.  I believe that this is critical in the development of diseases like Multiple Sclerosis.  Research has shown that people with MS respond to vasopressin antagonist drugs to heal their myelin deficits.  This tells clinicians that the chronic release of vasopressin to light stress is the key problem in this immune-mediated disease.

https://twitter.com/DrJackKruse/status/1609921221017190407

Is Nature's clue found in vasopressin molecular structure?  They are.  Vasopressin is a posterior pituitary hormone which means it has a direct connection to the retina and the SCN.  It also is directly related to the neuroimmune system.  It tells us sunlight is the electromagnetic stimulus that vasopressin reacts to.  Vasopressin is made in an area with no blood-brain barrier telling us that it is open to the environment's electromagnetic signal.  Vasopressin is made of 9 amino acids.  The amino acid sequence of arginine vasopressin (argipressin) is Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2, with the cysteine residues forming a disulfide bond and the C-terminus of the sequence converted to a primary amide. It has two clues it is a circadian qubit.  It contains two aromatic amino acids and it has a disulfide bond linked to its cysteine residue (re-read the orexin blog to understand the importance).

Mother Nature seems to want enough water in the system for the neurons in our brain to be able to anticipate it can follow the circadian rhythm of CSF production for the brain's glymphatic system, and that there will be enough to not compromise autophagy.

One of his key goals is to design a sensitive vasopressin test for healthcare workers to use for people with circadian arrhythmia in the Emergency Room. If levels could be assessed rapidly, it could help physicians to understand how the body is managing water, giving clues as to how to deal with various illnesses with blue light and nnEMF exposures.  In experimental models of cardiac arrest, vasopressin increases blood flow to the heart and brain and improves long-term survival.  But vasopressin release in excess seems to be one of the things that cause chronic injury to myelin in Multiple sclerosis.  This is why Big Pharma is developing vasopressin antagonists drugs to treat it.

Why? Our modern lights dehydrate us causing us to age faster and die sooner.  Sunlight hydrates our cells.

Middle-age serum sodium >142 mmol/l is associated with a 39% increased risk of developing chronic diseases  & >144 mmol/l with a 21% elevated risk of premature mortality. People with serum sodium >142 mmol/l had up to 50% higher odds to be older than their chronological age.  High serum Na is a proxy for your Light clock management behavior at the SCN level.

Until recently (2017), it was thought to only work in a classic, negative feedback loop: when we are dehydrated (bad matrix function at CCO), levels of vasopressin rise, which causes urine to become concentrated in the kidneys, freeing up more water to be used in the body.

Conversely, when we have too much water in our body, vasopressin levels decrease, and urine is diluted. What if that is not all that vasopressin does?

Vasopressin changes the possibilities that water presents to the quantum programs that control wound healing by altering charge density in coherent domains of water.  This adaptation is done by altering the epigenetic programs in cells.

Water is the quantum stage cells play on.  Water is created by cytochrome c oxidase in the mitochondria.  The spinning Fo head of the ATPase sits adjacent to the CCO. That spinning Fo head creates a magnetic field at the subatomic level. Inside a cell, water also has a magnetic dipole effect (negative and positive ends) because of the hydrogen and oxygen that make water up.

Hydrogen is positively charged, and oxygen is negatively charged. This creates a bar magnet effect in cells. These physical features are what help water networks respond to electromagnetism and waves of light.  If you look at the vasopressin molecular structure above you'll notice on one side of the disulfide bond there are a lot more negatively charged oxygen atoms.  This tips the magnetic flux one way to signal wounds should heal using the epigenetic programs mentioned in the video above and found in Becker's books.

I believe vasopressin is a highly negatively charged protein that is a 'qubit' (WBG semiconductive protein) for the quantum brain that changes epigenetic signaling in tissues.  Vasopressin is how we influence probabilities of future events in water using sunlight as a lever.

It seems organisms use vasopressin levels to predict and prepare themselves in advance for environmental changes that have selective advantages over those who cannot accommodate themselves until the changes of the environment have taken place to cause dehydration of mitochondria for some reason.  ALAN causes massive dehydration in the mitochondrial matrix.  Doing this long-term will shorten longevity by leading to diseases like MS.

In 2017 the same researchers found vasopressin does a lot more than they thought initially. They found that not only is there a vasopressin circadian feedback loop, but "it's also involved in feed-forward mechanisms. This is quite important in understanding from a chronobiologic perspective. They determined that this molecule is produced in the brain right before people go to bed WHEN IT IS SUPPOSED TO BE DARK, and during sleep, in anticipation of the dehydrating effect of sleep. During sleep, autophagy is supposed to be very active if you are healthy.  Vasopressin is normally released at 9 PM.  It is designed to offset the dehydrating effect of sleep.  Vasopressin is also known as an anti-diuresis hormone.

I believe vasopressin induces a negative magnetization in water networks.  What is negative magnetization?

When negative charges are added, we can find a temperature-dependent crossover of the DC magnetization from a positive value to a negative value of a material (cooled under a positive applied magnetic field) is termed the magnetization reversal or negative magnetization.  Becker found this flip in the DC magnetic field between sleep and wakefulness and between consciousness and general anesthesia.  Vasopressin helps us sleep when water creation is reduced.

Moreover, when you are recycling mitochondria during autophagy you cannot make any water at CCO. What happens if you cannot make water even in the sunlight because you've lost total control of autophagy because of chronic toxic blue light and nnEMF light stress?

The core skill of a successful Mitochondriac is error recovery in Nature, not failure avoidance from prior poor decisions.

There is only one way to repair that well. It means that we need SUNLIGHT IS MANDATORY to make water at CCO during the day. If you do not get enough or live at a high latitude and inside you need more water. If we do not get enough sunlight then we lose circadian feedback control of vasopressin and the entire water cycle in our body.  This is how lousy clock management leads to epigenetic disease by decreasing mitochondrial redox power.  You saw this in the petri dish picture above in the video.  A loss of redox power = disease state or injury state.  

So people who are incentivized by selling DDW need to be vetted.  They have not thought this out well from the Black Swan mitochondria perspective.


Our light choices can be seen in our labs if you know what to look for.  Our light environment trumps chronological age as an epigenetic driver.
Frequent shift work results in more urination for ANY AGE because the circadian gene Rev-Erbα controls the production of Cx43, which determines how much urine a bladder holds.

TL;DR: Poor circadian rhythm = More urination = more disease = FASTER DEATH COMES = THE RELATIVITY OF TIME MODELED.

Energy and light frequencies are the only predeterminants nature needs to change water's behavior in your cells. 

As the environment's frequencies and power density change so do the reaction of water in you. When you begin to realize how sunlight changes in different latitudes on Earth and in different cities because of 1G-5G footprints it should begin to make sense to you why you perform differently in differing locations. Water is made at cytochrome 4 called CCO. What if that process is disrupted by the environment? Is the fidelity of the signal destroyed? Will the oscillation pattern of the inner mitochondrial membrane also change? Is this why we lose the ability to fat burn with the 100Hz oscillation needed for beta-oxidation in alien environments? 

If so, does this affect how much water is made and how that water reacts within the metabolic cycles of the cell? You bet your ass it does. This is how nnEMF is operating to make you ill way below your ability to perceive it.

SUMMARY

I have found in my "internet guru career" those who are easily shocked about things or words I utter should be shocked more often in their life. This is why our brightest blazes of insight in life are really kindled by unexpected sparks of insight. Be unique and light people up because you are extraordinary in how you think.

Is drinking water post-sunset mandatory for outdoor living creatures based on what we've discussed here?   When humans tell you not to drink water might they be incentivized in trying to sell that belief (Boros and his DDW krewe in LA)

Canadian research showed that mammals tend to increase water intake just before sleep when sunlight is absent. Rather than being motivated by a physiological need for water, the drinking response was solely based on the animal's circadian rhythms.  The efficiency of your circadian mechanism is critical to this mechanism working as it is designed.  Sunlight creates water, darkness doesn't <----------BIG FREAKING DEAL ALERT.

Now consider hydrogen bonding networks in H20 are very dynamic. So dynamic that we cannot perceive how fast they adapt to light cells emitting.  These H= networks work at atto or femtoseconds when light photons interact with them. 

The fast adaptive behavior of these H+ networks in water, alone determines the dielectric constant of the medium they are within. The dielectric constant determines the refractive index of water.  Normal bulk water has a high dielectric value (78).  Things with high dielectric constants tend to be highly polar and water is.  Because of this polarity just about anything can be dissolved in water and made useful in some way.  Cells use this to build WBG semiconductors from carbon-based biomolecules in us. Water surrounds all of them. Low pH aqueous environments (inflammation) have excessive protons and a lowered dielectric value.  This means they do something to light inside our tissues.    Alkaline pH also changes the dielectric constant of water.  The other chemicals in the matrix, like exotic atoms used in WBG semiconduction in cells = Ca, Mg, Na, Cl, I, K, vasopressin, etc....can also alter the dielectric values in the mitochondrial matrix.  Oxygen does too.  This changes the spectra of UV light emission in cells and this is how epigenetic processes are driven by non-linear optics.  


They only create light in the UV spectrum.  Why did cells choose this?  Because UV light is the only part of the visible spectrum of light that can undergo non-linear optical transformation.  When you are at the beach this is sensing UV light at the classical level.  This is how people tend to understand things.  That is not how cells understand things.  When size and shapes change inside of organelles and compartments in cells you know light is the lever doing the changing of shape.  This is when you should realize as a classical biologist you are leaving thermodynamic levels and touching the quantum level of processing in cells.



Light at the beach discussed above only discusses sunlight in the classical world.  That is important to understand but in no way does it explain life, or what cells are doing below the cell level with light they are pumping into all electronic states in the system to build complexity from chaos, and order from it.  This is akin to using optical tweezers to move atoms around to get them to do what you want them to do. 


When light emitted from our cell hits water it alters its dielectric value (78-160) and this changes its refractive index and viscosity. The inside of your mitochondria becomes a gel-like piezoelectric flexoelectric quasicrystal.  Only quantum mechanics can tell its secrets when water and light change their physical states below the cell level.  


Each photon of light emitted has a frequency and that frequency has very specific, sensitive, and precise jobs to do.  Cells specialize in the photons they create because of the atoms they use in WBG semiconduction.  This changes how they process energy and information that send to your nucleus where DNA is.  DNA is an antenna for the light carried in cell water.  The smallest things in you make the largest difference in decentralized medicine & health.


When a cell is de-polarized (action potential)  it is deformed by water movements,  and potassium is released. A loss of K+ changes the VUV-IR-A emission of the cell.  This normally causes a glial cell to swell and the neuron's UV light emission is changed.  This change is picked up by genes related to the POMC complex in the hypothalamus.  This change in light emission causes a volume change in the adjacent neuron (astrocytes).  When size and shape change in a cell what does this signal?  

When water moves, it changes the refractive index of bulk water in the extracellular compartment of the neuron to create a large coherent domain of water within the neuron and below the myelin level. The astrocytes work as a giant drainage system for water, which uptakes potassium ions in regions with high potassium, and sends them to regions of lower potassium ion concentrations. The change in light emission precedes the release of vasopression.  Vasopressin changes how the drainage system operates at the AQA gates in neurons.

Vasopressin or antidiuretic hormone, which is made in the hypothalamus and is sent via its neural tracts to the posterior pituitary gland, allows the brain controls the flow of water to activate itself in accordance with the stimuli that it currently faces. Any trauma to neurons causes its release. Light stress is a big one mammals used 65 million years ago.  Normally vasopressin is controlled by circadian stimuli. The sun normally controls the release. Artificial light is a light stressor. It causes the release of vasopressin outside of the circadian mechanism and this leads to havoc = inflammation.

Fact: Blue light/nnEMF dehydrates cells and raises blood glucose and insulin because they stop H2O production from the mitochondrial TCA cycle. Why is this a big deal? Neurons absorb and release water when firing information via their action potentials. When H2O is missing in action so are neurological functions/capabilities.  This has a big time effect on hypothalamic POMC neurons. Check the link here.

Bai, Ruiliang. Brain-active transmembrane water cycling measured by MR is associated with neuronal activity. Magnetic Resonance in Medicine. https://doi.org/10.1002/mrm.27473

The gist of this paper is that neurons absorb and release water when they relay messages throughout the brain and peripheral nervous system. Tracking this water movement with imaging technology may one day provide valuable information on normal brain activity, as well as how injury or disease affects brain function.

The study appeared in Magnetic Resonance in Medicine.  Just how devasting is artificial light on water flowing in neurons?  4% of the world has autoimmune diseases related to the blue light hazard.  There are just over 100 human autoimmune diseases that afflict humans.  What if I told you light stress mediated via POMC is the real cause of all autoimmune diseases?  

Current functional magnetic resonance imaging (fMRI) technologies measure neuronal activity indirectly by tracking changes in blood flow and blood oxygen levels. Neurons communicate with each other by a process known as firing. In this process, they emit a slight electrical charge as an enzyme moves positively charged molecules — potassium and sodium ions — through the cell membrane. In the study, when researchers stimulated cell cultures of neurons to fire, they found that the exchanges of potassium and sodium ions were accompanied by an increase in the number of water molecules moving into and out of the cell.

Water movements only occur in the CNS/PNS via water channels that are made up of aquaporin 4 gates. This is going to become important later in the explanation of various diseases (MS). EVERY brain disease and EVERY autoimmune disease is tied to malfunctions in this mechanism

Remember that when water leaves a neuron, it carries a larger negative charge, and this charge induces an increase in the coherent domains in water networks inside the cytoplasm of the neuron. When the size of the coherent domains increases, it increases the optical efficiency within the neuron and outside the axon beneath the myelin where the interfacial water resides.

Remember that it is this interfacial water where Robert Becker found the regenerative DC current. This is why circadian biology and sleep are directly linked to regeneration. It all has to do with the scattering of light in water in neurons.

Ask yourself this: Is it biologically possible to predict the effects of lifetime exposure to electromagnetic, chemical, and physical agents that are not part of the biological experience of man given what we know about the butterfly effect?

If you do not fully understand light will you ever come to realize how important water is to life?


Evidence-based science has divorced itself from nature's evidence.

Quantitative evidence-based science is used to remove uncertainty by transforming it into a probability for algorithms so that mathematical modeling can play the ritual role of haruspices. This epistemic governance arrangement in science is today in crisis.
The primacy of science today is to adjudicate political issues and it is having massive collateral butterfly effects on public health.
They must pass through an assessment of the level of maturity and effectiveness of the various disciplines deployed. The solution implies abandoning dreams of prediction, control, and optimization obtained by relying on a limited set of simplified narratives that linear thinking scientists and clinicians can understand to define the problem and moving instead to an open exploration of a broader set of plausible and relevant stories that define the real issues at hand.

Get your light right....

The refinery Nature built in your cells is worthless if you don't feed it the energy it needs...

CITES

Mae-Wan Ho, Fritz Albert Popp, Ulrich Warnke Bioelectrodynamics and biocommunication 1994, p. 21

https://medicalxpress.com/news/2023-01-good-hydration-linked-healthy-aging.html

https://medicalxpress.com/news/2019-03-younger-nightshift-workers-shown-pee.html

https://www.nature.com/articles/nature19756

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400257/

http://www.photonics.com/Article.aspx?AID=41237

QUANTUM ENGINEERING #23:  CIRCADIAN CLOCK MANAGEMENT

Comments

Today's lesson on quantum biology: https://twitter.com/DrJackKruse/status/1641891940693168146

Dr. Jack Kruse

This comment comes all the way from Nova Scotia, Canada… I now understand (sort of) why I didn’t get up once to urinate while I was vacationing in Mexico!

Paula

Dear Laura, I find this item of most interest to my line of thinking. Having been to the Amazon Rainforest of Ecuador to investigate and learn the ancient practices of Shamanism, my eye caught this reference regarding Rome, and Haruspex, I have heard of the practice of entrail examination for such purposes, but never the actual word for it. Thank you. Now, the brain gears are spinning as to what else am I unaware of. You reference a Greet term for the similar practice which brings added meaning to the phrase "foie gras". Your command of these more ancient practices is not on the normal menu for required reading. So, this grasshopper is interested in how you meandered into the forest of such learning and any reference books that might assist me in uncovering some of the flat stones in the river. As well, what really interests me is that information which addresses the issue surrounding our so-called written word... and how that went from the ancient "clay tablets" of Summer, to and through Egypt folk law scribed onto papyrus, vellum, Hebraic Scrolls, and eventually found its way to the desk of Mr. Guttenberg, with a translation of biblical importance, via a letter from "said" Pope, and then onto the frontier of enlightenment, where it resides this day. For me and my house, well, our ancestry goes back to the Paleo caves, which have remnants in Spain and the caves in Lascaux France. Then there are those caves yet to be uncovered - discovered, before the final vote is in. I have had the pleasure to at least see the reproduction cave in Lascaux up close and personal. The main reason for my inquiry is that I am just tired of being "had" by the ones in charge of the game. History seems to always be written by those who become "king of the mountain, first." In addition, I did buy the Maverick video to enjoy the detail that went into the actual writing and production. I am very appreciative of the people who go out of their way to educate and support others in the journey of life, as Jack does, and the actor in Top Gun Maverick.. https://www.youtube.com/watch?v=IrA22Kifgx0

michael john moreau

Here is an epic blog article I put out years ago to teach you how to reverse skin atrophy from solar disuse. It describes how to build your solar callus naturally to offset the blue-lit/ nnEMF world we've built around us. This technocratic world is destroying our biological blueprint. Your solar callus not only offers protection but is an ideal way to absorb all frequencies of terrestrial sunlight properly to get light into your system build wellness and improve your immunity. Building your skin up to handle the sun is the first step in properly structuring water in you to become quantum coherent and energy efficient. Our skin tones are tied to our solar callus and are perceived as the most healthy and attractive to humans. We now know that red and yellow skin tones make you appear more attractive and send visual wireless signals to other retinas and brains that your immune system is becoming programmed properly and optimized for health. Being pale is not a sign of wellness contrary to popular dermatologic speeches. Being pale = the largest organ in your body has atrophied. Having too much vasopressin released via the retina = you'll atrophy your brain and this will also assist in atrophying your skin. Even animals besides humans use their solar callus to draw mates. Folks who spend time in the sun can change their surface color by assimilating certain frequencies of sunlight to take red tones because IR-A light increases our RBC's production when our skin is hit with sunlight it undergoes dermal pooling to make our skin flush with blood. When the sun has powerful UV light shining on our skin and eyes (latitude-based), more oxygen is found in our blood changing its color to a deep red due to the increased amount of oxygen in it. From a biological/anthropological perspective, this signals health and vitality and high redox potential to members of our species who see us in nature. The use of sunscreen is the most common form of modern skin atrophy in humans. It isn't mining. https://www.patreon.com/posts/13077291

Dr. Jack Kruse

Very wise deduction Conor

Dr. Jack Kruse

Thanks for this post Jack. Interestingly when a patient develops brain death after a neurological insult, vasopressin levels drop precipitously. If the patient is to become an organ donor then synthetic vasopressin if infused in order to preserve organ function. Traditionally this beneficial effect was thought to be due to its effects on blood pressure, however Noradrenaline which produces similar blood pressure effects does not preserve organ function in the same manner. Could it be that the vasopressin, as well as maintaining BP, also has an effect on the mitochondrial water and cell integrity and thus organ function. Thanks again Conor

conor mcgrath

Haruspex - (Wikipedia) "in the religion of ancient Rome, a haruspex was a person trained to practise a form of divination called haruspicy, the inspection of the entrails of sacrificed animals, especially the livers of sacrificed sheep and poultry. The reading of omens specifically from the liver is also known by the Greek term hepatoscopy."

Laura Kissmann


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