HYPOXIA #28: YOUR GUT HAS A MAGNETIC TRANSISTOR LUKE

LUKE’S PRESCRIPTION: Where observation and epiphany collided at this years member event.

IgA responds to native magnetic fields and this links it to seasonal viral illness and to gut abnormalites. How does this occur?

There is a clinical correlation between an allergic patient’s ability to resist the development of symptoms that would have resulted from an allergenic challenge, the magnitude of geomagnetism at a geographic site, and (3) the amount of solar energy falling on that site. It is suggested that the digestive membrane has an electronic gatekeeper that “decides” electronically which molecules to allow or not allow to pass on to the absorptive surface. The unique bipolar structure of secretory immunoglobulin A (IgA), having a central secretory piece and the resultant unique electronic function of this polarized molecule, allows it to function as an electronic transistor, producing an electronic gatekeeper in the form of an electronic sieve.

High-gradient magnetic fields (HGMFs) have steadily gained the increased attention of researchers from different disciplines, such as cell biology, cell therapy, targeted stem cell delivery and nanomedicine because magnetic fields change cell structure and size. Recent theoretical framework has provided a fundamental understanding of the effects of HGMFs on intracellular processes. It appears altered magnetic fields have huge impacts on IgA creation and destruction. This science highlighs new directions for the study of living cell machinery: changing the probability of ion-channel on/off switching events by membrane magneto-mechanical stress, suppression of cell growth by magnetic pressure, magnetically induced cell division and cell reprograming, and forced migration of membrane receptor proteins. By deriving a generalized form for the Nernst equation, we find that a relatively small magnetic field (approximately 1 T) with a large gradient (up to 1 GT/m) can significantly change the membrane potential of human cell and thus have a significant impact on not only the properties and biological functionality of cells but also cell fate.

^^^^^  This is the most detailed model of a human cell to date, obtained using x-rays, nuclear magnetic resonance, and cryoelectron microscopy data sets.  Source and Credit: Transformation of the Cellular Landscape through a Eukaryotic Cell, by Evan Ingersoll Ingersoll Gael McGill ~ Digizyme's Custom Maya Molecular Software----Biología Al Instante

Current antibody tests for COVID-19 test only IgM and IgG, and assume that IgM represents a recent infection, while IgG will represent a recent or distant infection. IgM comes first, followed by IgG. IgM disappears rather rapidly, while IgG stays elevated for a very long time. Therefore, IgM suggests recent infection whether IgG is present or not, while IgG alone suggests an infection in the more distant past. In the first week, there are nearly twice as many people who are positive for IgA to the spike protein than those who are positive for either of the other antibodies. IgA continues to be most prevalent in the second week, and it is almost as prevalent as IgG in the third and fourth weeks. IgM is never the most prevalent, and it drops off in the fifth week just like IgA. Only IgG remains prevalent in the fifth week. IgA antibodies were five times more effective than IgG antibodies at neutralizing SARS-CoV-2, the coronavirus that causes COVID-19.

The patients whose IgA had the greatest ability to neutralize the virus were the ones who had the highest levels of IgA against the spike protein.  this means those who can harness the magnetic flux of the sun best have the lowest risk of C19.  It also means these are the people who won't have gut issues from other causes.

Secretory immunoglobulin A is the dominant antibody isotype in mucosal secretions and plays an essential role in defense against pathogenic microorganisms bacterial and viral. However, even in the absence of infection, the body produces approximately four grams of IgA daily, more than all other antibody isotypes combined. Much of this IgA is secreted into the intestinal lumen, where it binds to and ‘coats’ specific members of the gut microbiota—the trillions of bacteria/viruses that constitutively colonize the human intestinal tract.

The gastrointestinal mechanism responsible for sorting molecules that were to be absorbed or rejected appeared to be related to the subject of electronics. The sorting process could be explained by the existence of an electronic sieve created via a massing of electronically enabled secretory immunoglobulin A (IgA) molecules, each acting as an electronic transistor. This electronic transistor function of secretory IgA can be achieved because of its bipolar structure and unique mid-secretory piece.

Secretory IgA plays a crucial role in shaping the composition and function of the gut microbiota in animals. It appears IgA responds to the varying magnetic fields on Earth between day and night.

Selective IgA deficiency (sIgAd), defined as a serum IgA concentration of less than 7 mg/dl with normal levels of serum IgG and IgM in subjects greater than four years of age, is the most common primary immunodeficiency in humans. Its incidence varies by geographical region, ranging from 1:700 in individuals of European descent to 1:18,500 in Japan. Location on Earth is linked to magnetic field strength variation. While IgA deficiency is often described as “asymptomatic,” sIgAd subjects exhibit increased incidences of infectious, allergic, and autoimmune disorders including inflammatory bowel disease. Secretory IgM can partially compensate for the lack of IgA in sIgAd subjects but not completely. Latitude and location seem to be the key to understanding the seasonality or the risk of electromagnetic pollution in many diseases.

UNCLE JACK’S TAKE HOME FOR LUKE: It appeared that the higher the geomagnetic properties of the area you live in, the more resistant the patient was to known allergens.  It appears if you live in a state with a lot of gas or oil deposits where drilling or fracking occur the more likely you will be to have gut issues. If you want an antidote move to the rim of the crater in PDC and Tulum and see how your symptoms respond. You might become able to turn on your electronic IgA transitor properly. 

The gut mitohacker should investigation using the USGS color aeromagnetic anomaly map of the contiguous United States should be a top priority. 

You should expect a sunset effect and seashore effect because of how magnetic flux varies at these times daily. You will crash at sunset and you will do better at the seashore with respet to all your allergens. 

At the seashore or at a water fall you get a huge "Lenard effect". This is when net negative ions are added to the air. This makes you more sensitive to magnetic flux and should improve your symptoms. An increase in ambient atmospheric negative air ions clinically appears to have a salubrious effect on a patient’s ability to successfully deal with a challenge from a known food allergen or from an altered microbiome. 

Those with gut issues or weakened immune system should struggle with Faraday cage effects. If you use devices or a field-free room (Faraday cage) you might get worse. Within minutes after entering these rooms I have noticed over the years individuals experienced weakness and severe fatigue as a result. This told me IgA was their problem.

It appears to me as if the energy of the sun is capable to changing the magnetic suceptibilty of the gut and immune system. Observation of several of the Kruse Longevity cases over the last two years have given me this insight. 

The final piece of the puzzle came for this October 2020 when I observed Luke over 4 days. I saw an amazing effect of a hurricane in the Gulf on Destin Fla Gulf and then observed changes at Morrison Creek and began to put things together. The eureka moment happened during a small speach from Luke in front of many where he came apart.  Sometimes we have to come apart to fall back together.   

I realized that the sun’s magnetic flux was being absorbed in a kind of electronic “alimentation” that provided free energy to reverse entropy and allow for the accumulation of properly sized particles on one side of the digestive membrane, thus allowing secretory IgA to act like a kind of Maxwell’s demon. 

Was this an evolutionary mechanism that animals developed to capture free solar energy just as plants developed photosynthesis as their mechanism for capturing free solar energy? I now suspect that secretory IgA is such a device that enabled this energy-capturing process to take place in the gut by acting as an electronic transistor to sculpt the microbiome and its immunologic response.  Could this a be a magnetic control gate for the brain?  

Might gut IgA be the brain's main protector.? 

IgA cells that originate in the gut play a role appear to have neuroprotective properties against diseases associated with neuroinflammation, such as meningitis or viral infection.

The membranes surrounding our brains (dura) are in a never-ending battle against deadly infections, as germs constantly try to elude watchful immune cells and sneak past a special protective barrier called the meninges. In a study involving human autopsy tissue, researchers at the National Institutes of Health and Cambridge University have shown that some of these immune cells are trained to fight these infections by first spending time in the gut.

It appears gut-educated antibody-producing cells inhabit and defend regions that surround the central nervous system.   Without a proper IgA response the brain becomes attacked and mental and cognitive changes become more likely. 

The central nervous system (CNS) is protected from pathogens both by a three-membrane barrier called the meninges and by immune cells within those membranes. The CNS is also walled off from the rest of the body by specialized blood vessels that are tightly sealed by the blood brain barrier. This is not the case, however, in the dura mater, the outermost layer of the meninges. Blood vessels in this compartment are not sealed, and large venous structures, referred to as the sinuses, carry slow moving blood back to the heart. The combination of slow blood flow and proximity to the brain requires strong immune protection to stop potential infections in their tracks.

The immune system has invested heavily in the dura mater. The venous sinuses within the dura act like drainage bins, and, consequently, are a place where pathogens can accumulate and potentially enter the brain. It makes sense that the immune system would set up camp in this vulnerable area to protect its Ferrari engine.  

IgA cells had not been shown to reside in the dura mater under steady state conditions.  Now we know they do.  

A recent study by the NIH (Cite two) discovered something surprising: there were many immune cells previously educated to make antibodies against specific microbes and viruses. These antibody-producing cells, called IgA cells, are typically found in other barriers such as the mucous membranes of the bronchial tree of the lungs and gut.

Pathogens present in the gut were important in educating meningeal IgA.  

This new data provide more compelling evidence that the brain is protected by immune cells that are educated in the gut and lungs.

IgA is a magnetic transitor that needs to be present and active to repair the gut and brain.  Where you live matters deeply in this electronic dance with Nature.

 CITES

https://www.nature.com/articles/s41598-019-49923-2

“Gut-educated IgA plasma cells defend the meningeal venous sinuses” by Zachary Fitzpatrick, Gordon Frazer, Ashley Ferro, Simon Clare, Nicolas Bouladoux, John Ferdinand, Zewen Kelvin Tuong, Maria Luciana Negro-Demontel, Nitin Kumar, Ondrej Suchanek, Tamara Tajsic, Katherine Harcourt, Kirsten Scott, Rachel Bashford-Rogers, Adel Helmy, Daniel S. Reich, Yasmine Belkaid, Trevor D. Lawley, Dorian B. McGavern & Menna R. Clatworthy. Nature