NokiMo
Dr. Jack Kruse
Dr. Jack Kruse

patreon


CPC #42: WHY WILL 5G DESTROY SULFATION AND CAUSE LEPTIN RESISTANCE IN HUMANS

Did you know AM-noon solar exposure has another hidden benefit?  Terrestrial sunlight has major effects on our colony of mitochondria to squeeze the semiconductive mechanism in the IMJs in our colony mitochondria.  This allows the 30,000,000 million volts charge in mitochondria to be transformed to a DC electric current in the circuit in our blood.  When our blood is fully powered, blood does not clot fast, and our red blood cell morphology becomes very smooth and the hemoglobin chains become piezoelectric to change their electric abilities to carry oxygen to mitochondria.  The other hidden benefit of solar exposure in your blood is that things that have increased sulfation levels in blood products are more water-soluble.  This is why people with significant COVID ICU stays clot their blood too easily.  Sunlight creates serotonin in our blood platelets and this makes them less attractive to one another.  This reduces our ability to clot.  People who lack sun, clot more.  People afflicted by nnEMF/blue light also clot more.  The lack of solar exposure also has another intended side effect.  It lowers circulatory system sulfation which affects the hydrophilic abilities of proteins in our blood.

It sulfates many chemicals in our bodies.  Why is this important?  Elemental sulfur acts like a qubit to charge the human battery using sunlight FASTER to increase the capacitor effect in our cells by making the water in our blood act like a true plasma.  The size of an atom correlates to its power as a qubit.  It also tells us something about its conduction band size.  This size of the conduction band tells us if the semiconductor is a wide band gap one or a low band gap one.  Solar-powered blood plasma acts like Triple AAA does to your care.  It can jump your car when it is DEAD.  Psychiatrists do not realize they do this when they use lithium in bipolar patients.  This can create huge problems in bipolar patients in strongly lit environments leading to bad outcomes.

Sulfated Vitamin D3 is made from specific frequencies of sunlight in the AM that process has little to do with calcium homeostasis.  Most allopathic and functional medicine doctors focus on the effect of Vitamin D and calcium homeostasis.  The quantum clinicians go way deeper than this.

Chronic blue light and nnEMF exposure UNSuLFATE your blood and proteins in your body and this lowers the amount of light energy you can bury in water and the cells in your body.  This makes your energy inefficient and if it goes on long enough it will make you LEPTIN resistant.

Un-sulfated Vitamin D contains the ability to regulate calcium homeostasis in the blood. You should realize a low vitamin D level will cause you to absorb LESS calcium in your gut, not more.   It will also raise the amount of unsulfated LDL cholesterol in your blood while causing the retinol-binding protein to rise and your B2 (riboflavin) levels to fall off a cliff.  If this goes on long enough melatonin, serotonin, and NAD+/NADH level at cytochrome one also become markedly abnormal and this indirectly slows the methionine cycle.

When the methionine cycle slows down you become  NET COLLECTOR of heavy metals in your BODY.  This does not even mean your environment has to be filled with heavy metals.  It means you lose the ability to handle their clearance of them because you've lost control of sulfation.  5G and blue light are the REAL REASON so many are heavy metal toxic and no one appears to know it.

HOW DOES THIS HAPPEN?

Sulfated Vitamin D is created best by AM sunlight when the color temperature of sunlight is below 6500K.  This is a huge teaching point.  The picture below shows you how blue light varies diurnally.  Today’s blog is about small alterations in your light environment lead to massive tissue-level changes in you.  When you cannot use our sun's plasma CORRECTLY to sulfate your lipids and proteins, you do not allow the atoms of sulfur or phosphorus to act like qubits to charge your quantum batteries.

Cholesterol and Vitamin D3 are nearly identical in chemical structure. Most people do not know this.  Sunlight naturally sulfates these things.  The only difference in both bio-molecules is a single double bond in the second ring of the cholesterol backbone. This gives Vitamin D3 one less hydrogen atom than the closed ring of cholesterol. After reading Tensegrity 6 that should make you think a lot more carefully about atomic details.  One hydrogen is the only difference at the atomic scale. Here you will see the wisdom of Tensegrity 6 play its role. Hydrogen is the ultimate chameleon for the sulfation and differentiation of cholesterol and Vitamin D3.  What does it do?  Vitamin D3 is synthesized from cholesterol in the skin upon exposure to specific frequencies of sunlight. When this happens and calcium is normal in the blood serum, both molecules remain sulfated by melatonin.  DON’T FORGET THIS MECHANISM. THIS HYDROGEN INTERACTION WITH and WITHIN THE SUN IS HUGE to maintain the sulfation of lipids and proteins.

This is the basis of how a quantum dot battery is built in animals.

Cholesterol is the main non-visual photoreceptor of the skin and brain.  Winter cholesterol is in the LDL format.  Summer cholesterol is in the HDL format.  Why?  Summer cholesterol has more electrons in it to absorb more solar photons.

Sulfated vitamin D3 is made from UVB and IR light and sulfated cholesterol in a very complicated quantum dance using sunlight.  When UVB and IRA light are present, the blue light free radical signal within the terrestrial sun is ALWAYS tightly controlled by IRA light.  IRA light limits the free radical signal of the blue light hazard to control vessel vasodilation.  This means that melanopsin's effect on the skin and eye arterioles MUST be tightly controlled.   At the same time this occurs UVA light has the effect of making melatonin, serotonin, and NAD+ from tryptophan.  These proteins also are critical in the controlled process.  The controlled response of blue light in AM sun also interacts with other B vitamins.  ALL B vitamins are blue light chromophores.  Cytochrome two FADH2 is a classic blue light chromophore while cytochrome one NAD+ is a fluorophore protein that absorbs at 340nm.  Vitamin B2 riboflavin is critical in this quantum dance because it too is a blue light chromophore that needs to be programmed by controlled AM blue light in terrestrial sunlight to emit electrons to work properly in the methionine cycle and the methylation cycles.  B2 has three benzene-like ring structures with nitrogen associated with them much like chlorophyll and hemoglobin do for activation of the pi electrons (HOMO and LOMO actions) which act to make it the perfect blue light photon trap.

When your skin produces cholesterol sulfate, your blood cells become sulfated, and this helps augment the DHA in the RBC to generate a net negative charge to repel the net negative charge in EZ water in the blood plasma.  This improves the flow, by improving laminar flow, and it increases the motion of blood in the arterioles and capillaries of the skin by proton motions caused by UV and IR light in the sun.  The blue light and UVA light act in unison to vasodilate blood vessels in your skin in different ways.  Blue light uses melanopsin to do this, while UVA light uses nitric oxide to do this.  The reason this is done is to create an electric and magnetic field within the blood vessel to activate NO production from the glycocalyx of the arteriole wall and the arterial wall in a controlled fashion.  The quanta of light controls this process.  These actions all work in concert to allow massive amounts of cholesterol to be bound to be sulfated.  This makes cholesterol more water soluble and has more electrons.  When this occurs cholesterol does not have to be tightly bound to LDL particles made from the liver.  As a result, LDL cholesterol drops.  High LDL cholesterol is a marker for quantum clinicians that sulfation is defective in patients.  The link is the amount of electrons in the HDL   If your liver doesn’t have to make so much LDL, the LDL goes down naturally.  At the same time, your blood pressure also declines naturally because sunlight also controls the voltage gates on your RBCs, platelets, and WBCs.  This controls how they act within your blood.  This determines the blood viscosity and its ability to clot.  Clotting of blood is effectively a quantum process.  When you clot unexpectedly it tells you the environment you were in 90-120 days ago is a bad. I can assess this in your blood plasma smear.

Sulfation by sunlight is a highly specific and sensitive quantum process where every single color of light is playing a role in your physiology which tightly controls how all of the proteins and lipids in your blood undergo sulfation and nitrosylation to act properly as the picture above shows.

Sunlight is like a natural calcium channel blocker in your skin.  5G and nnEMF raise your BP and cause clotting because blue light and nnEMF interfere with calcium homeostasis in the cell as the picture below shows.   Calcium channel blockers act to lower blood pressure by increasing proton flows in blood vessels.

WHAT ARE SOME MORE DETAILS IN THIS PROCESS?

5G is going to ruin sulfation and nitrosylation of your skin, gut, and eye because it will affect surfaces first because of how these waves ruin the topology of these surfaces. It is a prediction I made about the engineered 5G RF portion of the wavefronts because of its pulse rate and polarization. Now we have more data on why this prediction was made.

Sulfated-Nitrosylation is the covalent attachment of a nitric oxide group (-NO) to cysteine thiol within a protein to form an S-nitrosothiol (SNO). Sulfated-nitrosylation has diverse regulatory roles in bacteria in the microbiome, yeast, and plants, and in all mammalian cells. This process is almost always associated with the massive liberation of molecular hydrogen in the gut when this process occurs. The process of parsing H+ from deuterium in the microbiome controls the growth of species in the human gut because of the effect of deuterium to control the growth of the microbiome.

This process is run by three gasotransmitters and thus operates as a fundamental mechanism for cellular signaling across phylogeny and accounts for the large part of NO bioactivity in the human gut. This would have been the topic I was going to speak about in Vermont in 2019 but I changed plans and instead am heading to Munich Germany for Flowfest July 5-7, 2019.

How do you heal a gut in an electromagnetic polluted city using this basic science? Might it be wise to eat seasonal foods with nitrates (Epi-paleo Rx) and then get in the sun to boost your exercise performance?  Yes, it does.

Maximal nitrates and sulfur-containing amino acids come from seasonal vegetables only grown in the SUN and not in the artificial light of a warehouse. It also is found in meats made in many of the countries of Europe.

This is why charcuterie is a staple for me because nitrites added to meat are not damaging but quite helpful if you go outside. When you don't go outside in the sun, that's when you have problems with nitrates.  You can see this laid out in citation one below.

Sulfur groups come from the sulfur-containing amino acids methionine/cysteine/homocysteine/taurine of animals foods and the hydrogen comes from the microbiome of the gut and interact with the sunlight stimulus made via the skin, eye, and gut as I laid out in my Vermont 2017 talk.

Our gut makes over a liter of hydrogen a day and some of this gas links up to the sulfur recycled from foods to make H2S in blood. H2S in the blood is a gasotransmitter.  Sunlight determines the amount of hydrogen your microbiome makes.  Humans average the creation of 1 liter of hydrogen a day by the microbiome that senses the sunlight.  This amount of hydrogen made is reduced if your gut does not sense the sun's light.  The type of hydrogen also must be controlled.  H+ versus deuterium is a big factor here in the development of fatty liver disease.  The amount of hydrogen and sulfated amino acids you consume determines how good your methionine cycle and methylation cycles will be in the sulfation and nitrogen biology of your tissues.  IT HAS ZERO TO DO with your SNP and SAP profiles on your 23andme testing.  This is unknown in the functional medicine guru world because they have no understanding of how light controls the biochemical process.  This blog is the basis of what I was going to say in Vermont this year if I was invited back (2019).  Since I am going to Poland and Germany instead you get the guts of the talk here on Patreon today.

H2S gas is made by the microbiome and limits the power of NO made by UVA to vasodilate our arteriole and capillary beds in the skin, eye, and gut surfaces. H2S is also a huge substrate for sulfate (SO4) production in humans. Activated neutrophils in your blood under the power of sunlight can generate sulfate from H2S DIRECTLY using sulfur as a quantum dot while virtually all cells contain the enzymatic machinery to oxidize H2S to thiosulfate in a 3-step process in which sulfite is an intermediate substrate. Sulfite can also likely be generated from H2S via endothelial nitric oxide synthase (eNOS) which is why the post above is critical in understanding the microbiome.

HOW DO EMFs FROM THE ENVIRONMENT INTERFERE WITH THIS PROCESS?

The calcium efflux of 1G-5G networks and its associated blue light causes excess calcium directly in and around the cell and in its local environment. So with respect to RBCs (above), it also means that the creation of ALIEN electric and magnetic fields from 5G and not the sun will also affect the surface sulfation of the blood vessels.

Peroxiredoxins are the key peripheral circadian controller of RBCs that remove CpG Islands liberated from damaged mitochondria that cause hypermethylation and heavy metal accumulation in humans.  This comes from the nnEMF damage (RF mostly) which induces fragmented DNA and mtDNA that enter the blood when nnEMF is destroying cellular biology. Tight control of RBC circadian cycles links RBC antigen clearance on their surfaces to the innate immune system via a protein called complement protein number 4 (C4).

RBCs become more permeable to toxins in a 5G blue-lit world in this case and as a result, the RBC ages faster, and more antigens pass through the circulatory system.  The older a RBC become the less sulfated they are and the less sulfated your entire body becomes.  This drives METAL accumulation via the GUT.  This degrades melanin which chelates and gets rid of these metals.  This also drives biotoxin illness because C4 controls the antigen clearance of fungi, mold, and Lyme disease.  These people all have low levels of alpha MSH because they are all melanin degraded and have poor solar redox.  They never should be told to detox, because none of them have any redox power in their tissues.  This is really what happens in all mold and biotoxin diseases. It is not the mold or toxin that is critical in this case, it is the REMOVAL of the nnEMF field that is critical to get right. Most of the clinicians out there never get this advice to their patients or the public.  This is why 5G RF causes leptin resistance in humans QUICKLY.   This is a TOPOLOGIC effect of radiation in humans that is outside the visible spectrum of light.

All of these mechanisms of nnEMF field exposure alter melanopsin biology in the blood and arteries to a chaotic release of nitric oxide (NO) within cells and in arteries to cause disease when it occurs chronically and affects mitochondrial function when other frequencies of sunlight are subtracted from this photic dance.

The increase of nitric oxide and H2S is a chameleon event in the blood plasma. Endothelial nitric oxide synthetase has a quantum superposition effect on sulfur atoms in the skin, arteries, blood, and gut to protect us from dangerous nitrogenous groups in these antigens.

This means that any pulsed or polarized non-native man-made electromagnetic signal can have a variable non-linear effect on sulfation and nitrosylation pathways in any of these organs.

I covered this topic in my epic February 2019 webinar Q & A because I planned on releasing this blog today.

It can result in therapeutic effects or detrimental effects in the blood plasma depending upon the nnEMF stimulus. This will lead to highly variable chaotic mitochondrial energy flux and fidelity signal dynamics. This is very damaging to the matrix and directly affects what biochemistry can or cannot occur. This is one reason why non-thermal electromagnetic fields (PEMF) are increasingly used in medical therapies, but they are being used without any proper understanding of how they truly operate.

Today the sellers and purveyors of these devices think and believe that their RF/microwaves effect is always beneficial therapeutically in a wildly variable world of surrounding nnEMF. THIS IS PURE FALLACY AND MARKETING BULLSHIT.

Moreover, they fail to realize that this eNOS switch in cells is very sensitive to any variable PEMF RF pulse. This is why PEMF devices need to be strictly avoided in a 5G world. Yes, that includes all the Oura rings and PEMF devices pushed by BEMER and Dr. Havas based on the latest NTP study on RF radiations released on 11/1, 2018.

For example, if one is in an environment that fosters chronic nitric oxide release via chronic LIGHT STRESS implies there will be a relative lack of sulfation of the skin, arteries, gut, and RBC and this would favor the activation of the reactive nitrogen species of chemicals. This is particularly devasting to the microbiome because NO and H2S work in unison to control the constitution of the microbiome under the power of terrestrial sunlight. Humans no longer live under terrestrial sunlight and this is why their microbiomes are being destroyed by the modern world this changes their brains and arteries and ages their blood faster.

In fact, we now know that nitric oxide can also interact with the superoxide pulse (OO-) created in cytochrome one (NAD+/NADH) from altered mitochondrial function to create peroxynitrite (ONOO-) to do further damage. This is why people with gut and microbiome conditions relapse so often in toxic nnEMF environments loaded with blue light. Most doctors are not sophisticated enough yet to understand that things like SIBO and adrenal fatigue are adaptative and not pathologic symptoms tied to altered and highly variable EMF fields that their patients live in.  The defect is always in the brainstem at the PVN and its outflow tracts that innervate the celiac ganglia.

It has been found that when peroxynitrite breaks down, it creates reactive free radicals and oxidative stress within cells and this likely leads to many of the symptoms of Cardiovascular disease and neurodegeneration on longer timescales.

In this way, both atherosclerosis, CV, and neurodegeneration can be thought severe chronic adaptive mechanisms employed by cells that have developed an innate immune allergy to nnEMF.

HOW DOES METHYLATION TIE INTO THE QUANTUM DANCE?

In humans who have the MTHFR C667T polymorphism, all of the elevated homocysteine (sulfur-containing amino acid) is concentrated among people who have poor riboflavin (B2) status. Blue light toxicity results in the heavy metal collection because this slows down the methionine cycle naturally in humans. This is why understanding what free retinol does in a blue-lit 5G world is uber critical. Blue light causes flavins to emit electrons when they are in solution. In humans, this causes a real problem in our blood and our arteries now that we found melanopsin in our arterioles in 2014.  Melanopsin is the second most important non-visual photoreceptor in man behind cholesterol.

The free radical gasotransmitters help control the flow of hydrogen and deuterium (H+/D) to help control sulfation in your body.

How do you ask?  Here is where the physics geeks get some juice.

Sulfite, wherever it is generated, can be acted upon by the ubiquitous enzyme, sulfite oxidase, to generate sulfate = SO4. Given the body’s constant need for SO4 to build heparan sulfate, to carry out phase II detoxification in the liver (metals), maintain proper blood viscosity (RBCs and EZ) to prevent clotting and make sure the 93% of water in the blood plasma maintains its proper optical refraction state (270nm), and many other quantum actions not appreciated by functional medicine, It becomes obvious that any reduction in sulfate availability necessitates a “workaround,” a compensatory shift by the body.   The gut provides the workaround.

H2S produced in the gut microbiome via sulfur-forming bacteria, symptomatic though it may be, will diffuse into the blood and a portion of it will ultimately be oxidized to sulfite and then sulfate, via these mechanisms just described above. Your microbiome is built to liberate hydrogen gas to sulfate your body.  That is its key purpose.  How many of these colonies you have is dependent on the sun you get or do not get.  That is what its main function is. So if your molecular hydrogen breath test is high all it means is you cannot absorb the hydrogen your gut biome makes. The amount of hydrogen your microbiome creates is QUANTIZED by the light your microbiome SENSES via your skin and blood compartments. That is how counterintuitive the gut really is.  This is also why using molecular hydrogen machines and pills is not wise.

There are many reasons that sulfate might be in short supply, but by far the most common one is a LACK of sun on your skin. Today the introduction of technology supersedes this cause in my opinion.  Rest assured there are others that many of the functional docs will try to sell you CRAP for but they will never tell you about the sun because it is free.

The presence of strongly hydrated, kosmotropic anions like sulfate (SO4^2-) results in decreased 1H/2H exchange.  This suggests less free water, decreased protein solvation, and increased protein stability is likely ongoing inside of you whereas increased 1H/2H exchange is found in the presence of weakly hydrated, chaotropic anions (for example, ClO4-), correlating with increased protein solvation and decreased protein thermal stability.


Sulfate is a well-known kosmotrope in the Hofmeister series in humans and this means that it forms a gel-like liquid crystalline structure inside of cells that is used in a variety of ways.   This is how bulk water in your blood plasma becomes a magnetohydrodynamic plasma that wirelessly connects the sun to your mitochondria.  Your tissues become optimally sulfated when this process is not interfered with by man's use of technology.  This is another topologic change that will damage man today and no one seems to know it.  Now you do.

The terms 'kosmotrope' (order-maker) and 'chaotrope' (disorder-maker) originally denoted solutes that stabilized, or destabilized respectively, proteins and membranes; thus chaotropes unfold proteins, destabilize hydrophobic aggregates and increase the solubility of hydrophobes whereas kosmotropes stabilize proteins and hydrophobic aggregates in solution and reduce the solubility of hydrophobes. Sulfate stabilizes proteins in our blood plasma when the sun hits our skin and eyes.

CITES

1. https://www.sciencedirect.com/science/article/pii/S1089860314004510

2. https://people.csail.mit.edu/seneff/London2014/SeneffHeartDisease2014.pdf

3. http://www1.lsbu.ac.uk/water/hofmeister_series.html

CPC #42:  WHY WILL 5G DESTROY SULFATION AND CAUSE LEPTIN RESISTANCE IN HUMANS

Comments

This is an outstanding read! I wish I had discovered your work sooner. Now struggling with CIRS/MCAS/MCS/EHS, and desperately trying to find a solution to heal.

Lori Ann

Redox over detox.

Dr. Jack Kruse

Epic post doc! Thank you ❣

NIKOLAOS PETRIDIS

Janette, copy and paste into a word doc. That's what I do

Ann Boudreaux

You'd have to ask Patreon

Dr. Jack Kruse

I've been printing most of my research to avoid the phone and computer now. My skin hurts and I continue to develop eczema that seems to come and go despite my efforts; I am now very tan. Is there a way to print info from here?

Status Nominal

I got bit by a tick. Anything natural you recommend? I’m trying not to do antibiotics.

Alexander Guerra

...and I am planning to be there and listen & interact and download some sunshine data :-) looking forward to meet you in person Jack!

Du Ku

I'm guessing its that getting more AM sun will allow you to absorb more UVB later in the day, not that the AM light sulfates better than other sunlight. (with clarification from Dewey L.)

Jason Gookin

I'm planing on speaking......

Dr. Jack Kruse

Jack, what are you planning to do in my country (Poland) this year? We met briefly in Vermont last year if you remember - I am creating E.V.E. Electromagnetic Vitality Engineering.

Pawel Wypychowski

My genetic test said I had a SUOX SNP- which may have been why I used to feel bad after eating high sulfur foods- somewhat like the pseudo-allergy you are mentioning. I do not believe the SNP crap anymore. Since I have been getting our in the sun and following the Jack plan-- sulfur containing foods don't bother me.

Lisa Mancin

Where can I learn more on how AM light specifically helps moderate LDL cholesterol?

Jason Gookin

Seneff does not get deep into anything about light. HDL is critical in making D3. LDL is devoid of electrons = no photoelectric effect.

Dr. Jack Kruse

my pleasure.

Dr. Jack Kruse

very possible.

Dr. Jack Kruse

So would broken circadian rhythm, lack of sun, and excess exposure to nnEMF cause someone to have a pseudo-allergy to sulfur containing foods such as garlic and onions? I believe I have a colleague who this is happening to. Interestingly enough, one of the changes I've noticed since following Dr. Jack: I no longer cry when cutting onions...

David Labentowicz

thanks so much for this! Exactly what I was looking for especially the melanopsin article talking about light and blood vessel relaxation! This and CPC 15 ought to be great for a hematologist - dude you are so smart:-) I'm going to eat rumaki for breakfast:-)

Penelope Pappas

So if you have high LDL cholesterol sunlight is necessary to sulfate it to create D3. If UVB and IR light sulfate cholesterol and this is present in mid-day sunshine, why is AM light so important? I'm missing why AM is more important than mid-day. I missed where Seneff differentiates between AM and other sun

Jason Gookin

You mentioned coming to London this summer?... if you dont i will see you at flowgrade, or maybe both fuck it

Sean Waters

And why food... doesnt... matter.

Sean Waters

This is how the circadian mechanism is the controller for all our processes.... without it, nothing works.... this is why MTHFR isnt a problem if you rise and fall with the sun....

Sean Waters

To understand sulfation you must understand folate metabolism to restore redox detox pathways. The most reduced form of folate 1 Carbon unit, 5-methyl-THF, has a unique cellular fate, the remethylation of homocysteine to form methionine. 5-methyl-THF is produced by the cytosolic NADPH-dependent activity of methylene tetrahydrofolate reductase (MTHFR) and consumed by the cobalamin (vitamin B12)-dependent enzyme methionine synthase (MTR) . Mammalian cells can also regenerate methionine from homocysteine in a folate-independent manner using betaine (trimethylglycine, a product of choline degradation) via the enzyme betaine-homocysteine methyltransferase (BHMT). Expression of BHMT is limited to LIVER and KIDNEY (Pajares and Pérez-Sala, 2006), whereas widespread methionine synthase expression may enable homocysteine remethylation throughout the entire body. Homocysteine remethylation is of particular physiological importance because methionine is the substrate for S-adenosylmethionine (SAM) synthetase. SAM, the reactive methyl carrier, is the second most common enzymatic cofactor after ATP and plays a major role in epigenetics; it is critical in natural metal removal as redox power rises, and in biosynthetic processes including phosphatidylcholine, creatine, and polyamine synthesis; and sulfur metabolism (Finkelstein, 1990, Mudd et al., 2007, Su et al., 2016). In fact, phosphatidylcholine synthesis from phosphoethanolamine is likely the largest 1C sink in adult mammals and consequently the largest source of S-adenosylhomocysteine (SAH) (Stead et al., 2006). Changes in methionine concentrations lead to changes in the ratio of SAM to SAH that impact many methylation reactions including histone methylation (Mentch et al., 2015). The methionine cycle is slowed tremendously when deuterium leeches into the matirx via the broken circadian control of UCP-2 which causes COX-2 amplification. Methionine cycle is subject to the KIE of deuterium. The SAM/SAH ratio is tightly regulated by metabolic mechanisms including inhibition of MTHFR by SAM (Kutzbach and Stokstad, 1971), inhibition of the SAM-consuming enzyme glycine-N-methyltransferase (GNMT) by 5-methyl-THF (Yeo and Wagner, 1992), and sequestration of 5-methyl-THF by cytosolic serine hydroxymethyltransferase (SHMT1) (Herbig et al., 2002, Stover and Schirch, 1991). In mice, SHMT1 loss increases, and SHMT1 overexpression decreases SAM levels (MacFarlane et al., 2008, MacFarlane et al., 2011).

Dr. Jack Kruse

Not until their diets stop working and the supplements dont make a difference..... and is coming Jack, its coming.... #5G

Sean Waters

correct......when will they get it?

Dr. Jack Kruse

So once again, this isn't a food story.... it's an Environment story...……..

Sean Waters


Related Creators