Science gets interesting when you link it to life. Recently on my Patreon blog, I have been linking a story of how deuterium links to life to make a difference in the reality we observe. Deuterium is not a bad thing all the time. In fact, when it comes to receptor biology, drug effect, neurotransmitter release, fecundity you begin to see there is no shortage of ways in which an extra neutron perturbs and helps life by altering the lifespan of a molecule.
This is why life is incredibly complex. How a small simple change in a proton can really change many things we take for granted that bio-chemistry believes is true. When you add a neutron to protons many things change in biochemistry in ways we fail to account for. A two-fold mass gain decreases the bond length and increases bond strength. We fail to realize that temperature affects how hydrogen reacts hydrogen bonding networks suspended in an aqueous environment.
This ultimately changes a number of physical and chemical properties, including molar volume, polarity, electron donation, Van der Waal's forces, dipolar moment, and lipophilicity. For example, deuterated caffeine is known to elute faster in the lab on a gas chromatograph mass spectrometer. This means this kind of coffee and can a much larger effect of caffeine on its adenosine receptors in the brain.

This means deuterium in the wrong or right place in a molecule can change the reality of what could happen.

It appears the body has a tight quality assurance control program for how it uses and does not use deuterium over H+. A coffee bean is a seed of the coffee plant and the source for coffee. Coffee is a C3 plant. This means it has the most deuterium content based upon how photosynthesis parses deuterium using chloroplasts. Despite the classification as C3, coffee plants may display some interesting features concerning leaf anatomy and photosynthetic rates. It is the pit inside the red or purple fruit often referred to as a cherry. Just like ordinary cherries, the coffee fruit is also a so-called stone fruit. Fruits of plants are loaded with deuterium to control the growth of an immature plant into the adult form.
With deuterium laced coffee, a biohacker might even imagine trying to capture nature's most elusive super buzz by drinking it and then turn around and sell that to an unassuming market to create a super addicting product. The same is true for pills, Rx, and supplements and foods. In fact, depending on which of caffeine's methyl groups were originally deuterated by the manufacturer's processing, the cytochrome 450 enzymes that kick off its transformation in your liver (ultimately to formaldehyde) would likely balk at the enzymatically more resistant C-D bonds. This will delay the formation of some metabolites, creating a relative preponderance of others leading to effects that one would not see with standard non-deuterium laced coffee. The coming age of quantum biology holds a cornucopia of effects we ignore today that have massive effects. These effects can defy common intuition and common sense.

Did you know adenosine is the key signal for the human brain to enter the sleep phases where heteroplasmy rates are lowered? Did you know that heteroplasmy rates are lowered when we deuterium deplete our tissues? Did you know that deuterium is an isotope of hydrogen??? Do you know that the molecular formula for adenosine is: C10H13N5O4 Guess what happens if those 13 hydrogens are more deuterium and less H+?
You cannot sleep........and the more of those hydrogens that are dueterium the closer you get to INSOMNIA and no ability to regenerate your tissues? You'll believe you need a supplement pills the more deuterium you collect and you'll get worse if you listen to them. Did you know warm water collected deuterium because of its kinetic isotope effect? Did you know coffee has caffeine in it? Did you know caffeine reduces sleep pressure (which is supposed to start low in the morning and peak shortly after sunset) and delays melatonin onset (Burke et al., 2015). Did you know caffeine is an adenosine antagonist? This means it ruins sleep! Could it be that caffeine in warm water increases deuterium content in the water you're drinking while adding more adenosine molecules in your body ruining sleep? Could this be why people who drink a lot of coffee can't sleep and think they need melatonin supplements to sleep too?
Just because you did coffee before without any issues matters little because you body has never faced the coming onslaught of 5G. That is why what you've done before as a mitochondriac might have to be completely retooled soon.

Did you know that the accumulation of adenosine loaded with protium and not deuterium in the brain throughout the day is thought to be a chemical mediator of sleep pressure? Did you know that caffeine use also delays and reduces melatonin action? Did you know melatonin pills augment the glycemic response in cells driving insulin higher and increase ubiqutin levels and leads to mitochondrial swelling? Did you know when mitochondria swell in your eyes because of the pills that it thins your retina? Did you know that in the AM nature says we're supposed to have SUNLIGHT and FOOD not MELATONIN pills because the pills thin our retina and sunlight and protein thicken it and keep it normal?

Did you know a high protein AM meal optimizes the Vitamin A cycle in the retina? Did you know all opsin in the eye are bound to an retinol (Vitamin A)? Did you know Vitamin A defects are associated with all diseases linked to a broken circadian mechanism? Coffee is often associated with the development of adrenal fatigue by functional medicine docs on an adrenal stress index from a 0G-4G world. How does this happen? It destroys adenosine and nitric oxide function in the microcirculation. One works in daytime and the other works at night time. Adrenal fatigue links the light environment to the paraventricular nucleus in the brain (PVN). The PVN increases the sympathetic stress response via altered light spectrums.

Deuterium depletion is enhanced by the effects of high altitude and colder temperatures to stimulate heat release in mitochondria making high altitude (5000m >) glacier water some of the most naturally deuterium depleted waters in the world, with concentration levels between approximately 130-145 PPM.
You’ll notice when you embrace cold in your environment higher amounts of saliva produced after cold water immersion. Does it have anything to do with deuterium depletion or the autonomic nervous system? Yes, it does. With cold exposure you will urinate more. If you checked the urine with a mass spectrometer you would see it had a lot of deuterium in it. Why? Urination is another parasympathetic process (vagal) because it facilitates heat release from mitochondria under cold exposure. Heat stimulate cells to use H+ in their environments over deuterium. The parasympathetic division of the autonomic nervous system functions with actions that do not require immediate reaction. A useful mnemonic to summarize the functions of the parasympathetic nervous system is SSLUDD (sexual arousal, salivation, lacrimation, urination, digestion, and defecation)
Sympathetic activation by using coffee can cause deuterium assimilation in the cytosol and matrix to affect the urea cycle and the TCA flux rate.
Light information is captured exclusively by the skin and eyes using specialized retinal photoreceptors and transduced directly to the SCN via a dedicated neural pathway, the retinohypothalamic tract (RHT). The skin and retina use the same opsins to signal light information to the brain. Each day the light-dark cycle resets the internal clock, which in turn synchronizes the physiology and behavior controlled by the clock.
The major biochemical correlate of the light/dark cycle is provided by the pineal melatonin rhythm. Under normal light-dark conditions, melatonin is produced only during the night, by using sunlight captured in biogenic amines during bright sunlight during the day to power the effect while ridding us of deuterium. Moreover, it provides an internal representation of the environmental photoperiod, specifically night length.
This pathways in the retina and skin also helps yoke the Vitamin A cycle in the photoreceptors to the environment in this way. Vitamin A and the B vitamins thiamine, niacin, and riboflavin are strongly fluorescent under UV light. This is why the B vitamins are used in the TCA cycle where NADH/NAD+ is a 340 nm fluorophore protein. These two cycles (Vitamin A and D) in the brain and skin become coupled correlated substrates that allow the brain to predict the future by trendsetting or 'thin slicing' light frequencies using photochemical cycles in out tissues. It does this by ordering hydrogen into its quantum spin state. Deuterium has a different spin number and magnetic moment and this is why it is handled differently than H+ under the power of sunlight.
Did you know coffee and melatonin pills ruin this coupling of melanopsin and Vitamin A in the retina and skin/fat? Did you know it affects the neuropsin UVA receptor in your cornea and skin that link to Vitamin A? Did you know a low melatonin level also cause an increase in heteroplasmy rate in the colony of mitochondria in you? Did you know the lower your melatonin levels the more you need sleep and AM sunlight exposure ? Did you know in the PM, if you have not experienced at least 8 hours of melatonin action on your mtDNA to lower heteroplasmy system wide, that more insulin MUST BE MADE? Did you know that excess insulin is not enough to maintain normal blood sugars? Do you think that is risk free?
SUMMARY
The risk benefit ratio for coffee is going to change in a 5G world. In a 0G-4G world coffee could be thought of as a potential benefit. In a 5G world it might be deadly because of the changes that a ruined circadian mechanism has on deuterium fractions in your mitochondria. You need to consider that as the technology networks change around you.
Today, coffee alone is a major cause of a circadian phase delay in humans. This should get you to realize that in today’s modern blue lit 4G environments that most of us should be avoiding a plant with high deuterium content. Few of us live under the power of the SUN. the sun depletes us of deuterium and blue light causes us to assimilate it. Coffee has a positive vibe to it in our world. Have you every realized that because of all of the above, maybe why we think we need that coffee? That need and desire is tied to how you use blue light and nnEMF to excess in your life. 5G is going to exacerbate this effect and not lesson it.
If you were wise, you'd back off of coffee now before you are combating 5G in your hacks.
CITES:
http://www.scielo.br/pdf/bjpp/v15n1/a03v15n1.pdf
Brett
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