Making an artificial sweetener from Tylenol and pee | Edible Chem

Nice.

Twilight Snarkle

Most small labs wont even have a fumehood. For me, there isnt just one item that I can think of. Its more like lots and lots of smaller things that add up in price.

Nile Red

I thought there was some clever ghetto way to do it. The machines seem expensive, though. What's the most expensive thing for a small lab? I'm guessing a fume hood.

Lindy

I'm glad you liked it!

Nile Red

Seriously cool video! Your reactions to the tea were great! I was surprised from your first impression that it was as dramatic as it was. Would be fun to reproduce the tests for the sweetness factor. But, also time consuming and expensive. Excited to see what other edible chem you cook up next!

wizardfusion

Very cool. How about making stevia by synthesis by sratch if possible. I use it a lot for coffee, etc.

Daniel Blake Shoemaker

With a melting point apparatus and a thermocouple.

Nile Red

Very interesting and cool video. How do you measure the melting point?

Lindy

Uhhh I need to re-render and uplaod. I accidentally deleted an audio section. Thanks for pointing it out

Nile Red

Long pause (2-3 sec) @ 1:38

Dror Kronstein

Lol nice! :)

Nile Red

Nice mugs, I have them too ;)

damn, thanks for point it out! I dont think ill be fixing it though.

Nile Red

There's a typo at 50 seconds, sodium hydroxide is misspelled as NaoH rather than NaOH.

Marc Ethier

lol, it mightve been closer to a 100th

Nile Red

Yeah, you put WAY more than 1/250th of a teaspoon in there. May I recommend using some of your patreon funds to buy a good digital milligram scale? :)

jason black

You can find some information here: :) <a href="https://pubchem.ncbi.nlm.nih.gov/compound/74066" rel="nofollow noopener" target="_blank">https://pubchem.ncbi.nlm.nih.gov/compound/74066</a>#section=Top <a href="https://www.google.no/search?q=4-Methoxyphenylurea&amp;gws_rd=cr,ssl&amp;dcr=0&amp;ei=G8EyWsG6IcTdwAKtlq2wDQ" rel="nofollow noopener" target="_blank">https://www.google.no/search?q=4-Methoxyphenylurea&amp;gws_rd=cr,ssl&amp;dcr=0&amp;ei=G8EyWsG6IcTdwAKtlq2wDQ</a>

Alf-Marius Dahl Bysveen

There is one that is slower. Ill probably put that one on my Instagram eventually

Nile Red

Hmm that is a good question and it is really hard to know. You can look it up on Google, maybe it's been done before. Changing small things like that can sometimes change a lot, and other times not change much.

Nile Red

What type of compound would you have made if you instead used methyl iodide in the first step making it a methyl ether. Would it still be sweet?

Well done, super interesting.

you are right for all your points. I didnt realize the p- error when i was making the diagram though. For the bicarb, it honestly didnt even occur to me that it would be neutralizing some acetic acid as well.

Nile Red

Sorry for my English though, I'm not from any English speaking countries. And I have some dyslexia, so literacy isn't my most powerful side!.. :)

Alf-Marius Dahl Bysveen

Interesting:.. One adult person needs 20-40 g of ducline to bring pretty severe toxic effects. Just for comparing, 10 g of saffron is seen as lethal for adults. :) Once again; a cool video you have made! ;) <a href="https://pubchem.ncbi.nlm.nih.gov/compound/9013" rel="nofollow noopener" target="_blank">https://pubchem.ncbi.nlm.nih.gov/compound/9013</a>#section=Safety-and-Hazards

Alf-Marius Dahl Bysveen

Cool video and a great ending. I love this video series. Even under laboratory conditions it sounds like comparing flavor intensity is still subjective (sweetness wrt sugar, Scoville units, etc.). The one exception that comes to mind is the bitterness of beer; IBUs report the concentration of specific bittering compounds by measuring the % absorbance at 275 nm. I'm a little surprised that there's no enzyme binding assay or some other objective measure of comparative sweetness. A couple of comments: 1) the leading p in p-phenetidine should be both italicized and lowercase. 2) The bicarb neutralization should also form sodium acetate from the acetic acid you hydrolyzed and then acidified in the previous steps.

love the crystalization on this one. wish there was an HD slo-mo :)