Heavy Metal Detox Protocol
Added 2022-03-22 03:06:56 +0000 UTCI had to lay out the mitochondria/redox overview prior to this latest protocol because dysfunction in either is the root of heavy metal accumulation in the first place. Without functional mitochondria, reduction-oxidation potential (glutathione, superoxide dismutase, catalase, metallothionein - enzymes that neutralize oxidation from and bind heavy metals for elimination from the body) does not have the cellular energy to function properly either. This plays into the methionine or methylation cycle as well as both folate and B12 are diurnal (natural light/total darkness)-dependent in their respective functions. The methionine/methylation cycle funnels into glutathione production as well.
So mitochondria and redox come before detox, and now hopefully you all understand why I say that. However, with the level of toxicity present today, additional detox support when necessary is ALWAYS helpful, while mitigating much of the inflammation and oxidative stress they produce, as well as aiding in elimination.
In my experience with mercury and aluminum toxicity from amalgams and hard drug addiction, many of the heavy metal detox protocols either worsened my symptoms acutely and long-term, redistributed the heavy metals into other organs, or they were unrealistically long over the course of years if not decades. I continued regardless because I didn't understand the complexity involved here regarding these eliminatory processes before meeting with my mentor and then teaching myself more about quantum/circadian biology and its influences on these processes. And I didn't realize there were more effective means of detox. Then I dove into Jack Kruse's work after CK began writing up reviews with his own perspective and gradually formed my own until I retested for mercury and found there was no longer toxicity present, nor do I ever experience any of the same symptoms I did after age 16 when I got the amalgams and was abusing hard drugs.
Definitely review and implement the advice in the mitochondria/redox overview first and foremost for a few months, but much of what I'm going to share is the complex interactions between nutrients and heavy metals. If you're experiencing heavy metal toxicity, you will greatly appreciate this approach and it wouldn't hurt to implement as it reduces the pain and discomfort of detox significantly. I'm not saying it will be completely comfortable, but it will make the process much easier on the body.
To summarize the overview briefly, optimize mitochondrial function and reduction-oxidation potential with sunlight/grounding and low EMF environment, minimize/eliminate blue light during daytime and especially after sunset (protecting both eyes and skin), lots of seafood, deuterium depletion to enable electron transport chain for glutathione/metallothionein production.
Implementing the zero-tolerance dietary framework and focusing on nutrient-dense whole food sources, including fiber to act as a binding agent to clear metals from digestion and bile excretion will reduce systemic inflammation and oxidative stress so that your body utilizes more of your micronutrient intake and cellular energy/ATP towards detox and elimination rather than simply managing the inflammation/oxidative stress from a poor diet. Obviously, this includes drugs as well. If you consume cannabis, coffee, or tobacco, make sure you know where it's grown as well as the soil quality and growing process. Grow your own if possible. These can also be sources of heavy metals, namely cannabis and tobacco, which can be inhaled directly into the brain once combusted. No Bueno.
You will require sufficient dietary intake for running the methionine/methylation cycle, the primary protocol of which can be found here and the addition to protocol here with additional notes. Just to quickly summarize, the B vitamins, folate (methylfolate/5-MTFR and folinic acid, must avoid folic acid), B12 (adenosylcobalamin and methylcobalamin, hydroxocobalamin metabolize into both forms, cyanocobalamin must be avoided), B6 (pyridoxine/P5P), riboflavin (riboflavin/R5P, requires iodine, molybdenum, and selenium for full functionality), choline (phosphatidylcholine, alpha-GPC, citicoline, choline bitartrate, lecithin), niacin (nicotinic acid/niacinamide), glycine, and trimethylglycine.
The glutathione cycle requires methionine, cysteine (N-acetylcysteine/NAC can be supplemented as well here, increases glutathione in the brain, just start low and slow in dosage as always), glutamic acid, glycine, magnesium, phosphorus, zinc, copper, selenium, thiamine, riboflavin, niacin, and pyridoxine/B6 for proper function, aside from the necessary cellular energy to run it all. This further highlights the crucial importance of a nutrient-dense whole food diet that includes sufficient animal proteins.
Circadian rhythm, sunlight exposure, and mitochondrial function is also important because melatonin specifically is one of the master antioxidant and detox agents within the body. CK has highlighted this many times, but here's a review on melatonin complexing with a number of heavy metals. Mercury, cadmium, antioxidant properties, and more can be found here.
More on endogenous heavy metal chelation and nutrient/dietary factors.
Selenium neutralizes and binds to almost every heavy metal for elimination: Mercury, aluminum, plus more. Contained in seafood, shellfish, red meats, eggs, and dairy primarily.
Silica and boron (example one and example two) do as well. Silica is contained in Fiji water and similar mineral waters and horsetail herb/extract. Boron is found in a range of fruits and vegetables, however, it's highly dependent on soil quality where they are grown. Boron may be best supplemented if unsure.
Molybdenum, found in legumes such as black-eyed peas and lima beans, ancestral whole grains, rice, nuts, potatoes, bananas, leafy green vegetables, milk, yogurt, cheese, beef, chicken, eggs, and organ meats, is an antagonist to copper in supplemental amounts and can aid in eliminating unbound copper. Zinc does the same, also found in the mentioned animal foods and oysters.
Iodine, from seafood, shellfish, seaweeds (nori, kelp, kombu, wakame), milk, cheese, yogurt, eggs, beef liver, chicken, and iodized salt, compete with and eliminate stored fluoride and bromine. Turmeric aids in protection against fluoride-induced neurotoxicity. Turmeric/curcumin also binds most any heavy metal, including iron and copper. Extremely useful spice.
Zinc supplementation in itself, ranging in 15-300mg dosages (stick to lower dosage end unless severely deficient and even then best to do so under doctor's guidance, is found to directly increase metallothionein within the body, but it's additional cofactors such as magnesium, IP6/phosphorus, glycine, cysteine/NAC, and protein from animal foods enable Metallothionein function even further, paired with sunlight of course.
Thymoquinone in Nigella sativa black seed oil improves metallothionein production. Go figure, huh? Benefits really don't end.
Codonopsis pilosula is another favorite adaptogenic tonic herbal medicine of mine, which contains plant metallothionein directly.
Milk thistle is a full-spectrum liver/gall bladder support herbal medicine, so of course it improves metallothionein production as well.
Cordyceps sinensis upregulates the expression of metallothionein and can be included to any heavy metal detox stack.
Seasonal soluble fiber (meaning seasonal fruits and vegetables) to bind anything eliminated via gut/bile, activated charcoal dispersed in water can also be useful for metals and deuterium accumulated in the gut.
Hodges RE, Minich DM. Modulation of Metabolic Detoxification Pathways Using Foods and Food-Derived Components: A Scientific Review with Clinical Application. J Nutr Metab. 2015;2015:760689. doi:10.1155/2015/760689
"hops, pomegranate, prune skin, and watercress... quercetin... sulforaphane in cruciferous vegetables... polyphenol/flavonoid-rich fruits and vegetables... (watercress, garden cress, and broccoli), allium vegetables, apiaceous vegetables, grapefruit, resveratrol, fish oil, quercetin, daidzein, and lycopene."
In essence, redox before detox, the body has evolved to take care of the issue for you.
Heavy metals have always been present throughout our evolution, most people just don’t have healthy mitochondrial function or redox because they’re disconnected from decentralized Nature and connected to centralized Mainstream Medicine and Technology.
In my experience, I’ve personally resolved mercury and iron toxicity (genetically hereditary hemochromatosis) in myself, then intentionally induced copper toxicity just to see how it felt before resolving that as well. I no longer experience any symptoms whatsoever.
Please let me know if you have any questions. I will be flying out to the new house tomorrow morning, so just had to finish up this article to share with you all. I will be much less active for the next few days, but will post up a couple more articles before the month's end as well as do a live Q&A on our Discord channel once I get settled in. Patrons will be the first to hear about updated coaching scheduling as I've gotten probably hundreds of requests since I began my moving process.
As always, love truth wisdom,
Daniel aka Grimhood