Anxiety/OCD Protocol (GABA Support Quantum Revitalization)

In the past, I've reviewed GABA/glutamate biochemistry and its role in all psychiatric/neurological conditions, especially anxiety and OCD, extremely extensively for several years now, but there were gaps in my knowledge missing. The key to filling these gaps was zooming out of the biochemical model and into the biophysical model. It took a bit for me to complete this new article because I wanted to ensure I filled any gaps possible in my newfound theories while finding references to support everything. The quantum picture I've discovered also explains why my vision protocol is so effective and how I resolved myopia and astigmatism (retinal degeneration) in myself, and now a small handful of others I've shared this knowledge more. This picture will be connected further below.

This gets EXTREMELY complex, well beyond common biochemistry, so I will do my best to put it all into my own words and simplify it all to the best of my understanding. There will be references included periodically if you would like to brave the research and read further. 

As you may know from my Twitter threads in the past, the biochemistry involved in anxiety and OCD is GABA/glutamate imbalance, cortisol/imbalance, adrenaline, and serotonin/dopamine dysfunction, with inflammation and oxidative stress playing a major role as well. The most important being balanced GABA and glutamate, cortisol and melatonin, efficient dopamine function biochemistry, and mitochondrial redox status, as this is what ties into the fact that anxiety/depression is the beginning stages of neurodegeneration altogether. The pathology of these psychiatric conditions is extremely similar to all neurodegenerative disease,, and that's what got me so interested in both subjects.

What I've recently connected to the quantum picture is that all of these receptor systems and cellular processes are connected to circadian biology/rhythm and mitochondrial function (redox status). Circadian biology and leptin/melanopsin function/sensitivity is coupled to cortisol/melatonin balance, GABA/glutamate, and dopamine/serotonin function. I outlined how leptin/melanopsin runs dopamine function and cortisol/melatonin in the recent ADD/ADHD protocol, but as a brief outline summary, leptin and melanopsin becomes dysregulated with sunlight (UVA/UVB/red and infrared light) deficiency, artificial blue light at night (ALAN), and non-native electromagnetic fields (nnEMF/5G/WiFi/Bluetooth, etc.) It is important to know that as tyrosine and tryptophan are aromatic amino acids with a benzene ring, they require UVA and UVB light spectrum to activate the enzymes that convert them into dopamine and serotonin/NAD+/melatonin respectively. The same applies to GABA and glutamate balance, glutamate dehydrogenase (GDH)  and glutamate decarboxylase (GAD) enzymes require not only UVA/UVB light to be activated and run efficiently, but also red/IR light. This just drives home the vital importance of full spectrum sunlight at key circadian periods. Light energy is what allows cofactor substrates and micronutrients to be utilized in enzymatic cellular processes that run your biology and biochemistry.

Quantum tunneling of protons and electrons plays a primary role in mitochondrial function and redox status, and how the biology handles DNA and RNA. When we begin to live an unnatural life and begin to fear the sun in favor of an alien sun, eating an alien diet, while bathing in nnEMF without the Earth's native EMF, a state of pseudohypoxia is induced by decreased oxygen levels and subsequent lower balance of NAD+ to higher NADH. This shifts triple state free radical production in the mitochondria to singlet state and increases intracellular Ph levels, which negatively influence the enzyme reactions that run all biochemistry. This crashes everything within the biology, to put it simply. Low electron to high proton ratio in the mitochondria contributes to cellular dehydration, inflammation, and dysfunctional mitochondrial function/redox status. When mitochondria become dehydrated and Ph shifts, 

When this occurs, we become more susceptible to the detriments of artificial blue light and nnEMF, which promotes calcium efflux from the cells and begins the cycle of GABA/glutamate and cortisol/melatonin imbalance, and glutamate excitotoxicity with mitochondrial dysfunction. Without this fine balance between these factors, psychiatric and neurological symptoms become apparent and exacerbate in correlation to this disconnection from nature's laws. Red/infrared light and the full light spectrum from sunlight is THE main factor that drives quantum tunneling, but so does cold exposure, exercise, ancestral whole-food-based diet (SN-2 position DHA from seafood/shellfish and animal brains), drinking quality non-fluoridated water, and total darkness at night (melatonin produced with healthy circadian rhythm) cools the body during sleep, allowing the mitochondria to form exclusion zone water and restart the regeneration processes (autophagy/apoptosis and neurogenesis/synaptogenesis). This is a major reason why cold thermogenesis has such a positive benefit.

It is common knowledge that trauma makes one more susceptible to psychiatric/neurological symptoms, however the reason behind this is because it severely downregulates the GABA receptor system, allowing glutamate and calcium to run rampant, and downregulation the parasympathetic nervous system, allowing cortisol and adrenaline to run rampant. This biochemistry makes one even more prone to circadian dysregulation, as GABA/glutamate and cortisol/melatonin run the sleep-wake cycle and neurogenesis ability. Due to the physical and emotional stress, micronutrient cofactors also become depleted, so it becomes an endless cycle one gets stuck in. This ties into why I call anxiety/OCD "sticky brain", as one becomes more prone to snap back into place with unsuccessful changes not addressing the correct factors in relevant biochemistry.

It goes even deeper than this. There are multiple components to the retina in the eyes, and how they process light to communicate with the brain, but here's a basic outline for my theory that ties quantum biology to GABA/glutamate biochemistry:

• It is currently understood that there is a connection between retinal degeneration (poor/damaged vision) and psychiatric conditions/neurodegenerative disease, but the exact connection and which precedes the other has yet to be determined. I believe it can go both ways for the reasons I've outlined above and will expand on further below.
• Müller cells make up the entire length of the retina/eye.
• Müeller cells are required to detox metabolic wastes, induce neurogenesis, recycle glutamate into GABA, and communicating light signals to the photoreceptors to then communicate that light to the brain.
• Glutamate in blood/serum is triggered by blue light, nnEMF, free glutamate from the diet, mitochondrial dysfunction, and leptin/insulin resistance = high blood glucose.
• I believe the glutamate in the blood is circulated into eyes via the blood-retina barrier and throughout body, then circulated out of the eyes and back into the blood. This is supported by Dan Oren, MD's work on syntonics, where he states 40-50% of the entire body's blood volume is circulated through the eyes every 60 minutes when exposed to light.
• When Müeller cells become damaged, they are unable to recycle excessive glutamate and the closest place it is communicated to is not just the rest of the retina, but the brain which then communicates with the entire central nervous system.
• Excessive glutamate is shown to damage the retina, including the Müeller cells. 
• Artificial blue light is shown to inhibit GABA function while also inhibiting neurogenesis potential. 
• Artificial blue light triggers all-trans-retinal formation in the eyes, which destroys photoreceptors and damaged Müeller cells (unable to complete retinoid cycle). These two cell types are tightly coupled and the photoreceptors provide light to stimulate glucose metabolism/oxidation in Müeller cells, eventually depleting the glycogen they preferentially run on, so they become damaged and oxidized as a result. Without the glucose to form lactate, they no longer have sufficient fuel to function.
• More on all-trans-retinol and the visual cycle. 
• nnEMF also destroys sensitive photoreceptors in the eyes, creating a feedback loop cycle of glutamate accumulation. nnEMF triggers voltaged gated calcium ion channels and the release of glutamate in eyes, brain, and the central nervous system.
• Artificial blue light also triggers elevated blood glucose which does the same to the retina and creates a leaky blood-retinal barrier.
• Blue light toxicity destroys the protective reflex of the pupil to contract or construct in light frequencies, increasing risk of damage throughout the entire retina.
• Glutamate accumulation in retina transports via diffusion and leaky blood-retinal barrier into astrocytes, microglia, etc. for another feedback loop cycle, which becomes harmful when unable to be recycled.
• Circadian dysregulation from sunlight deficiency and blue light/nnEMF toxicity plus all factors summarized below contributes to leaky gut and leaky brain, contributes to massive systemic inflammation and oxidative stress/peroxidation which adds more fuel to the fire.
• The entire retina and all cells that make it up, including Müeller cells, participates in the visual cycle or retinoid cycle (recycling all-trans-retinal back into 11-cis-retinol + more) which is only accomplished with the FULL light spectrum during the daytime and TOTAL darkness at night in vertebrae. This process is extremely energy intense so only photo flux from sunlight can accomplish the cycle.
• All of this research suggests that the full light spectrum of sunlight, beyond isolated blue light from tech devices, is required to regenerate the photoreceptors, opsins, Müeller cells, and retina via melanopsin (present in eyes and skin).

To summarize the main contributing factors to this GABA/glutamate imbalance shown to be connected to anxiety/OCD and all psychiatric/neurological conditions:

• Artificial blue light toxicity and sunlight deficiency
• nnEMF toxicity and native EMF deficiency
• Blue light/nnEMF disrupts SCN control of circadian rhythm, then hormone profile deficiencies or imbalance, via cortisol/melatonin imbalance (pregnenolone, progesterone, testosterone, estrogen, DHEA), these are inhibitory towards excess glutamate/calcium
• Dietary free glutamate (low glutamate diet shown to improve anxiety and PTSD in VETERANS, who I guarantee have seen much worse than the average citizen, here is a list of dietary sources of free glutamate: https://leavesoflife.com/glutamate-food-list/)
• If you are experiencing anxiety/OCD or depression, it is very likely you are consuming a number of ingredients from the list above, but depending on the severity of your symptoms, it may not be necessary to eliminate them all (although you should). The ingredients that primarily cause issues are listed under "Sources of MSG" and "Excitotoxic Food Ingredients"
• Inhibitory micronutrient deficiencies that are required for GABA/glutamate and cortisol/melatonin balance
• High blood glucose and leptin/insulin resistance from high carbohydrate diet out of season respective of latitude
• Deuterium accumulation from eating fruits, vegetables, grains, etc. out of season, inside living without seasonal exposure to the elements (cold), sunlight deficiency, and blue light/nnEMF toxicity triggers mitochondrial dysfunction and insufficient ATP for GABA/glutamate shunt cycle
• Ammonia from dysfunctional GABA/glutamate (GDH and GAD enzymes) shunt accumulation triggers glutamate receptor activation (this one is less common, but still a possible contributing factor when it comes to GABA/glutamate)
• Copper excess/toxicity and zinc deficiency (serum levels should be 1:1 optimally)
• General systemic inflammation
• Chronic infectionsnfections (lack of sun, which has antimicrobial and antiviral properties, and native EMF = poor immune system function)
• Gut microbiome dysbiosis/SIBO
• Low redox/mitochondrial dysfunction
• Drug addiction or dependency (medications themselves can also play a role when consumed chronically via receptor system downregulation, mitochondrial dysfunction, and micronutrient cofactor depletion)

Now that I've laid out a general outline for you as simply as I could explain it for the average person, let's get into what you should be doing to correct these "chemical imbalances" and manage your symptoms effectively.

• 1) You must see the sunrise and sunset on a daily basis to set the circadian rhythm and mitochondrial function/redox status. If it's cloudy, go outside anyway as you will still be absorbing light into the eyes and skin. Optimally, 30-60 minutes for each, but 5-10 minutes minimum. UVA and red/IR light is most notably present during sunrise, red/IR light during sunset.
• 2) Ensure you are grounding your bare feet to the direct Earth, hands too if possible, to allow sufficient electron transfer from the Earth into the body, as well as reduction of inflammation.
• 3) Ensure you are also getting midday sun exposure where UVB light is present. Vitamin D deficiency = low redox and blue light/nnEMF toxicity. Ensure you don't burn, so start with 5-15 minutes until solar callus is established. Red/IR light will also be present during this time.
• Melatonin is produced by all light especially sunrise and midday, but sunset is very notable at setting the circadian rhythm and the urge to sleep at a decent time. Ensure your bedtime includes the 10 PM - 2 AM golden hours where most detox and repair (as well as EZ water formation and deuterium depletion) occurs.
• Restoring melanopsin, melatonin, and leptin function by living a circadian compliant life regenerates the eyes, brain, central nervous system, as well as the enzyme processes required to balance relevant biochemistry and hormones.
• 4) If you work during the day, ensure you are taking breaks outside in the sun periodically. Spend as little time inside exposed to artificial blue light as you can possibly manage. Wear blue light blockers and cover as much skin as you can manage if you work on technology and/or in offices, and wear them anytime after sunset.
• 4.5) If you work a tech or office job, you especially must heed this advice and try to swap your schedule so you're seeing the SUNRISE most importantly, sunset if possible, then take 5-15 min. breaks periodically throughout the day to offset the blue light/nnEMF detriment. Pick up a portable red/IR light device if you can afford to do so to offset the present artificial blue light.
• Avoid night shift work at all costs. Your health is worth more than any amount of money.
• 5) Turn off artificial blue light and screens after sunset, or replace your light bulbs with red/amber bulbs or use candles/oil lamps if no small children or rambunctious pets around. Use for 2-3 hours maximum before preparing for sleep. Use Iris software on any computers or laptops, set a red light filter on any phone devices. Try to minimize artificial blue light and nnEMF exposure to the greatest extent possible during the daytime as well.
• Do not wear glasses, contacts, or sunglasses while exposing yourself to the sun, as the glass/plastic blocks 40-50% of infared light and a good deal of UV light, in essence making one blue light toxic inherently. Use common sense and wear them if you're performing dangerous activities or require them for work. You don't need perfect vision to sit/stand idly in the sun.
• 6) Ensure you have a fat/protein-heavy breakfast within 30-60 minutes of your sunrise exposure preferably, if not as close as possible. Try to have dinner at least 2-4 hrs before you go to sleep each night. Meal timing is important to circadian rhythm and cortisol/melatonin balance and function.
• Seafood/shellfish, animal brains, and/or pasture-raised eggs are a daily must to include in your diet for electron-rich SN-2 position DHA to regenerate the eyes allowing you to reset your circadian rhythm, brain/CNS biochemistry, hormonal status, EZ water formation, and mitochondrial function.
• 7) Begin to implement a resistance training protocol. Endurance training is optional, although recommended if you're not running endurance marathons.
• Sunlight, grounding, cold thermogenesis, cellular hydration, and swimming in natural bodies of water like the ocean act as Faraday cages against nnEMF. I also like keeping geodes around me as well when I'm using the laptop.
• Minimize artificial blue light and nnEMF to the greatest extent possible with all of the advice I've shared.
• Begin to practice cold thermogenesis whenever you can, even if it's just a cold shower, ice packs, or being outside in cold/snowy weather (50-55 degrees F is minimum temperature to trigger this benefit) 
• Ensure your diet covers the inhibitory micronutrients, supplement gaps if needed: Magnesium, taurine, DHA, iodine, selenium, zinc, molybdenum, potassium, chloride, bicarbonate, lithium, inositol, choline, glycine, B1/B2/B3/B6/B7/B9 (folate and intrusive repetitive thoughts)/B12
• Implement the zero-tolerance dietary guideline which covers many of the dietary sources of free glutamate
• Review the Gut Repair Protocol and Addition To article for restoring the gut microbiome and integrity
• Helpful supplements to address acute symptoms and contributing factors while you implement the above: Multiform magnesium, lithium chloride/orotate (low dose), l-theanine, taurine, NAC, zinc, myoinositol, IP6, black seed oil
• Helpful herbal medicines to address acute symptoms and contributing factors: Blue lotus, black seed oil, skullcap, magnolia bark, jujube, ku shen, gotu kola, bacopa, lion’s mane, polygala tenuifolia
• Coindentally, many of these nutrients also contribute to retinal regeneration and neurogenesis, both of which go hand in hand, as well as the antioxidant cofactors
• Aside from the connection between circadian dysregulation and the hyperactivation of the default mode network in the brain, psychedelics and ketamine are also shown to regulate the DMN (do not use if risk of mania or psychosis)

Now you can see why I unintentionally reversed myopia and astigmatism in myself, GABA/glutamate management is directly coupled to quantum biology. This is the link I've discovered to my Vision Protocol.

See previous GABA protocol here. I will be writing additional articles to expand even further as I learn more on this connection, but I believe this will be a lot to take in and observe the connections between both subjects. I fundamentally understood WHY GABA/glutamate management is so crucial on a biochemical level, but the quantum level filled any remaining gaps whatsoever.

Additional references:
Neves-Petersen, Maria & Petersen, Steffen & Gajula, Gnana. (2012). UV Light Effects on Proteins: From Photochemistry to Nanomedicine. 10.5772/37947. 

Bertani DE, De Novellis AMP, Farina R, et al. "Shedding Light on Light": A Review on the Effects on Mental Health of Exposure to Optical Radiation. Int J Environ Res Public Health. 2021;18(4):1670. Published 2021 Feb 9. doi:10.3390/ijerph18041670

Gottlieb, Ray & Wallace, Larry. (2010). Syntonic Phototherapy. Photomedicine and laser surgery. 28. 449-52. 10.1089/pho.2010.9933. 

Różanowska, M. and Sarna, T. (2005), Light-induced Damage to the Retina: Role of Rhodopsin Chromophore Revisited. Photochemistry and Photobiology, 81: 1305-1330. https://doi.org/10.1562/2004-11-13-IR-371

Holton KF, Ramachandra SS, Murray SL, Baron M, Baraniuk JN. Effect of the low glutamate diet on inflammatory cytokines in veterans with Gulf War Illness (GWI): A pilot study. Life Sci. 2021 Sep 1;280:119637. doi: 10.1016/j.lfs.2021.119637. Epub 2021 May 17. PMID: 34015284.

As always, if you have any questions, please feel free to ask.