CPC #16: QUANTUM BREATHING EFFECTS

The Bohr effect hinges around the electromagnetic allosteric interactions between the heme molecules of the hemoglobin tetramer.  The Bohr effect a decrease in the amount of oxygen associated with hemoglobin and other respiratory compounds in the inner mitochondrial membrane in the cristae in response to a lowered blood pH resulting from an increased concentration of carbon dioxide in the blood.  Recall that in humans, CO2 levels, and not oxygenation stimulate breathing rhythms in the brain.  

This effect is tied to a lowered blood pH (more acid = higher H+ or deuterium) resulting from an increased concentration of carbon dioxide in the blood.  As the exclusion zone (EZ) is built by the collision of sunlight with the water in blood plasma and in our cells, H+ is excluded from the quasicrystal lattice of the EZ,  and this increases CO2 to create headaches and cognitive decline in people.  This is why these symptoms are exploding now.  Most people live a life where too little sunlight is assimilated and this means the pH in the blood is no longer optimal.  The less sun you get the better your breathing mechanics must be to remain far from equilibrium.  This makes our cells act like a dissipative quantum structure.  

HOW DOES THE POWER DENSITY OF THE ENVIRONMENT ALTER THE BOHR EFFECT?

The higher the power density of nnEMF/blue light is the more dominant the Bohr effect becomes.  As the Bohr effect becomes more dominant, it becomes the key etiology for keto- adaptation.  This is a false narrative.   Fat oxidation from a dietary change results in the creation of water and CO2 in cells and the blood.  We forget this basic physiologic fact of life.  So, when you go ketogenic by fat burning, it massively raises CO2 levels.  Those levels stimulate breathing more optimally.  This means if there is not a resultant CO2 spike in your blood with a dietary change you know you have a serious heteroplasmy rate issue in your mitochondria.    

Cold exposure raises CO2 levels normally if mitochondrial function is decent.  If mitochondrial function is not optimized or you hack this in blue light you will notice higher spikes of glucose in your blood.   Moreover, the experience of the astronauts living in space, has taught us big time lessons.  In this environment,  nnEMF power densities is off the charts, it also raises metabolism of both fat and glucose simultaneously.  Blood tensions of CO2 are affected by the cardio pulmonary system or when mitochondrial metabolism is decreased and altered.  This is associated with an altered phosphate/oxygen ratio (P/O) and a lowered voltage on the inner mitochondrial membrane (called delta psi).  Since carbon dioxide reacts with water to form carbonic acid, an increase in CO2 results in a decrease in blood pH.  This results in hemoglobin proteins releasing their load of oxygen. Conversely, a decrease in carbon dioxide provokes an increase in pH, which results in hemoglobin picking up more oxygen.

H+ is hydrogen proton with its electron stripped.  Deuterium is a proton with a neutron in the nucleon with its electron stripped.  Both can act as a metal plasma in this state without their electrons.  The key difference between both is their magnetic moment.  We now know from research that the relaxation rate of water protons in a given tissue may become dependent on the interactions that ANY metal complex is able to set up with other substrates.   This is why we use gadolinium metals as contrast agents in MRI.  It turns out that deuterium can also act as a contrast agent in T1 imaging because of its kinetic isotope effect in hemoglobin.  This implies that deuterium content in our blood plasma may have a dramatic effect on how hemoglobin can operate to deliver oxygen and CO2 properly in humans.  Heavy deuteration from nnEMF power density would simulate pseudohypoxia in tissues in space or on Earth in environments loaded with nnEMF.  David Sinclair paper in December of 2013 linked pseudohypoxia to low NAD+ states and all diseases of aging.  This is consistent with what astronauts have experienced in space with regards to their health.  They all seem to age faster in space than Einstein's law's or relativity suggests.  

The magnitude of the Bohr effect is usually given by the formula Δ log (P50)/ΔpH.  Hemoglobin can bind to oxygen and to protons as the video above shows.  What the video missed is the effect of deuterium replacement with hydrogen in their cartoons.  Why?  Deuterium has a much higher binding affinity to hemoglobin and to oxygen than light hydrogen does due to its kinetic isotope effect.   

This means that the fractionation of H+/deuterium becomes very important.  Recall that in space the an increased power density of nnEMF favors deuterium assimilation in our tissues over H+ assimilation for many reasons.

This will have a huge effect on how metabolism in mitochondria work and it will also effect temperature changes in the blood necessary for a proper melatonin cycle and cortisol cycle in astronauts.  These are the key features of why space travel is so dangerous to humans.  

Here, P50 refers to the partial pressure of oxygen when 50% of hemoglobin's binding sites are occupied. The formula is obtained by plotting the logarithm of this measurement on a graph at various pH levels, yielding a line with slope equal to Δlog(P50)/ ΔpH

Interestingly, Bohr effect strength exhibits an inverse relationship with the size of an organism: the magnitude of the Bohr effect increases as size and weight decreases (mass increase).  This has massive implications for humans with more mass from a higher deuterium fraction in their bodies compared on a relative basis with light hydrogen. 

PROVOCATIVE SPECULATION  

For example, mice possess a very strong Bohr effect, with a Δlog(P50)/ΔpH = value of 0.96, which requires relatively minor changes in H+ or CO2 concentrations to cause seismic physiologic changes, while elephants require much larger changes in concentration to achieve a much weaker effect  Δlog(P50)/ΔpH = 0.38.  This means mice will not tolerate space or high power density environments well, but fatter larger animals will.  Could this be why the obesity epidemic is really happening?  Might it be a protective mechanism to the amount of nnEMF we are using for communication?

The key point to understand is that any tissue or animal with a higher metabolic rate will be subject to the effect of deuterium to a much larger degree than we would expect.  This is why Scott Kelly had so many issues with cognitive function in space when his CO2 levels were pushed to the limit by the CO2 scrubbers used in the ISS.  It also underpins why his return to Earth has not gone well.

The Bohr effect is tightly coupled to metabolic scaling laws of Kleiber (mito matrix kinetics) but animals that eat a ton of DHA PUFA who inhabit cold environments tend to break these quantum rules we have seen in the literature.  So far NASA does not seem to realize the benefits of seafood for human space travel due to the power density effect on the Bohr effect.

WHY IS SEAFOOD PROTECTIVE TO nnEMF?     

An exception to the otherwise well-supported link between animal body size and the sensitivity of its hemoglobin to changes in pH was discovered in 1961 in sea mammals.  Based on their size and weight, many marine mammals were hypothesized to have a very low, almost negligible Bohr effect. However, when their blood was examined, this was not the case.  This allows them to get rid of all their oxygen when they dive deep in water when oxygen is not present.  We know water is a natural Faraday cage and it transfer heat 24 times more than air does so this likely causes them to be the exception rather than the rule.  The cold anoxic environment are stimulating physiologic changes to make their hemoglobin hold onto oxygen with more affinity than would happen in air.  Cite 3 below goes into the complex chemistry why this happens.   This is why humans might want to keep a body of water close to them in a 5G world while doing their hacks or exercise.  They can use this effect as 5G takes hold.  

Another special case of the Bohr effect occurs when carbon monoxide is present in the environment or tissues. This molecule serves as a competitive inhibitor for oxygen, and binds to hemoglobin to form carboxyhemoglobin. hemoglobin's affinity for CO is about 250 times stronger than its affinity for O2, meaning that it is very unlikely to dissociate from Hb, and once bound, it blocks the binding of O2 to that subunit.  Methylene blue is very helpful in carbon monoxide poisoning just as it is helpful in heavy deuteration in the mitochondrial matrix.  CO acts with O2 in a very similar way that deuterium does with oxygen via its kinetic isotope effect.  D-O bond is 10.6 times stronger than the H+-O bond.  

How does cold improve immune regulation??? One fallacy I'd like to slay from the Internet is that it is brought on by breathing pattern. This is a false narrative built by Wim Hoff. It works on a bio-physical mechanism within the WBC's which are normally loaded with deuterium to help boost immune response. This means that WBC have more deuterium in them to raise temperature to affect immune function and proton flows.  So today I'd like to give you education on both sides of the equation. I truly like Wim Hoff and I love that he brings humans back to nature in the cold I just am not in love that he has no earthly idea why what he does works. 

Wim apparently doesn’t know:  that heavy “in and out breathing”, as he teaches is beneficial.  It is not.  This method significantly reduces carbon dioxide in the blood making blood more alkaline and that hemoglobin in alkaline blood has a harder time releasing oxygen to the tissues than in normal blood (which is slightly alkaline). 

Due to the Bohr Effect, hypocapnia causes cerebral hypoxia which sounds dangerous and opposite to what Wim Hof states in his classes. It causes headaches and cognitive haze that submariners and astronauts get.  Just two parts per million increase in CO2 can cause this in space.  NASA uses 2 ppm for its CO2 scrubbers and cosmonauts use 6 ppm for their scrubber’s causing problems for astronauts who return from the ISS in a Soyuz space capsule like Scott Kelly did last year.  This is why cosmonauts use much less water during re entry and take a ton of salt instead.  Astronauts drink a ton more water with salt but they need to rely on wearing a diaper during re entry because of the fluid shifts that occur when they come back into gravity and inside the magnetosphere from the vaccum of space.  Ironically, this difference in technique between space workers in Russia and the USA is a big tell why some people urinate too much at night and those who do not.  Wim’s breathing technique resembles what Kelly faced in his space return and also sounds similar to the childhood fainting game that aims to create euphoria or giddiness.

In humans, the primary urge to breathe comes from CO2 receptors in the brain when they sense that there is too much CO2 in the blood.  We are very sensitive to this and become more sensitive to CO2 when our cell membranes are DHA deficient.  It turns out we know that deuterium also cause massive turnover of cell membranes and depletes of DHA as well.  This maybe the key reason why seafood is irreplaceable in a 5G world.   It also maybe why NASA is now pushing its astronauts to take DHA supplements with them into space.  So far the supplements have not helped and I have a sneaking suspicion why is related to the deuterium content of the fish oil when it was manufactured.    Wim happens to be a vegetarian and a smoker.  Therefore he has little DHA and lots of CO in him.  This state is not the state of most of his clients and not too many of them know it.  This is why I would never go train with him.  I choose to do it the way nature built us to work.  But it does point out one great thing.  Cold is massive helpful to humans living on Earth surface now in a 4G world.  Wim gets this one very correct.

Therefore, being able to maintain a long breath-hold after heavy “in and out breathing” doesn’t mean that the body has been flooded with oxygen; instead the ability to have a long breath-hold is primarily because the urge to breathe has been lessened due to low CO2 signal in the blood. How cold immunity works is linked to deuterium motions between immune cells and blood plasma.  Moreover, it is related to the fact that immunogenic proteins in us are reacting to the power density of the environment around us, and this is what activates epitopes inside of us to increase immunity or decrease immunity.  This is why the power density increases of today are linked to autoimmunity and to autism in my humble opinion.  

When you know better, you can begin to do better.  

CITES

https://www.nature.com/articles/s41598-017-11288-9

https://www.ncbi.nlm.nih.gov/pubmed/23430994

https://www.sciencedirect.com/science/article/pii/S0006349599774266

Scott Kelly.  “Endurance”. My one year in space.  2017.